Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants. - Wikidata - awgldk - TriplyDB

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

http://www.wikidata.org/entity/Q42727745

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Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing data.Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion Frequency of undetected CYP2D6 hybrid genes in clinical samples: impact on phenotype prediction.Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.Multi-ethnic cytochrome-P450 copy number profiling: novel pharmacogenetic alleles and mechanism of copy number variation formation.Single dose, CYP2D6 genotype-stratified pharmacokinetic study of atomoxetine in children with ADHD Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children.Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes.Prediction of CYP2D6 phenotype from genotype across world populations Complexities of CYP2D6 gene analysis and interpretation.Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.Polymorphisms in CYP2D6 may predict methamphetamine related heart failure.CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.CYP2D6 and pharmacogenomics: where does future research need to focus? Part 1: technical aspects.Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.Comparison of genome sequencing and clinical genotyping for pharmacogenes.[Drug induced hepatotoxicity in targeted therapy for lung cancer].

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P2860

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

http://www.wikidata.org/entity/Q42727745

description

2010 nî lūn-bûn

@nan

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@en

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@nl

type

label

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@en

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@nl

prefLabel

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@en

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@nl

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FPHAR.2010.00121

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Frontiers in Pharmacology

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Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.

@en

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Andrea Gaedigk

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Anick Bérard

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J Steven Leeder

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Joseph S Bertino

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L Dianne Bradfordand

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Lazara Karelia Montane Jaime

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Victoria M Pratt

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P2860

Mechanisms of change in gene copy number

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.

CYP2D6: novel genomic structures and alleles.

An unequal cross-over event within the CYP2D gene cluster generates a chimeric CYP2D7/CYP2D6 gene which is associated with the poor metabolizer phenotype

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry.

DNA microarray technology in the clinical environment: the AmpliChip CYP450 test for CYP2D6 and CYP2C19 genotyping.

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.

CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.

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10.3389/FPHAR.2010.00121

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