Protein kinase C-theta mediates negative feedback on regulatory T cell function. - Wikidata - awgldk - TriplyDB

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

http://www.wikidata.org/entity/Q42728050

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Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis Protein kinase C signaling and cell cycle regulation The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition Signaling in T cells - is anything the m(a)TOR with the picture(s)?PKC-Theta in Regulatory and Effector T-cell Functions The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again Chimeric Antigen Receptor- and TCR-Modified T Cells Enter Main Street and Wall Street Investigative and clinical applications of synthetic immune synapses Role of T cell-nuclear factor κB in transplantation Treg functional stability and its responsiveness to the microenvironment The Novel PKCθ from Benchtop to Clinic Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod Antigen-specific suppression and immunological synapse formation by regulatory T cells require the Mst1 kinase Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells Protein kinase C in the immune system: from signalling to chromatin regulation Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells Autoimmunity in primary T-cell immunodeficiencies.CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation.Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.Ubiquitous points of control over regulatory T cells.Advances in graft-versus-host disease biology and therapy.Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells PKC theta ablation improves healing in a mouse model of muscular dystrophy.Embryonic stem cell-derived factors inhibit T effector activation and induce T regulatory cells by suppressing PKC-θ activation.First insight into the kinome of human regulatory T cells.Induction of multi-functional T cells in a phase I clinical trial of dendritic cell immunotherapy in hepatitis C virus infected individuals.Immune suppression and immune activation in depression Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.The variable hinge region of novel PKCs determines localization to distinct regions of the immunological synapse Toll-like receptor mediated modulation of T cell response by commensal intestinal microbiota as a trigger for autoimmune arthritis Progranulin: a promising therapeutic target for rheumatoid arthritis.Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity.

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P2860

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

http://www.wikidata.org/entity/Q42728050

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@en

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@nl

type

label

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@en

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@nl

prefLabel

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@en

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

@nl

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SCIENCE.1186068

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P1476

Protein kinase C-theta mediates negative feedback on regulatory T cell function.

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P2093

Alexandra Zanin-Zhorov

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Juan J Lafaille

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Keli L Hippen

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Maryanne Brown

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Yi Ding

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P2860

Human T regulatory cell therapy: take a billion or so and call me in the morning

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

The immunological synapse: a molecular machine controlling T cell activation

The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

Three-dimensional segregation of supramolecular activation clusters in T cells

Selective modulation of protein kinase C-theta during T-cell activation

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

Mechanisms of foxp3+ T regulatory cell-mediated suppression

Regulatory T cells and immune tolerance

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5976

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328

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Michael L Dustin

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2010-03-25T00:00:00Z

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42589155

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20339032

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2905626

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