about
Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptorsExcessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activityAltered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout miceAssessment of tribal bison worker hazards using trusted research facilitatorsProduction of the butyrylcholinesterase knockout mouse.Mass spectrometry identifies multiple organophosphorylated sites on tubulin.Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.Contributions of selective knockout studies to understanding cholinesterase disposition and function.Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse.Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice.Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse.Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse.Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity.Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice.Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice.Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice.Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase.Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP.Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents.Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice.Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.Prolonged toxic effects after cocaine challenge in butyrylcholinesterase/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans.Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmisSocial marketing campaign promoting the use of respiratory protection devices among farmers.Role of Acetylcholinesterase on the Structure and Function of Cholinergic Synapses: Insights Gained from Studies on Knockout MiceThe butyrylcholinesterase knockout mouse is obese on a high-fat dietWhole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesteraseAdaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout micePhenotype Comparison of Three Acetylcholinesterase Knockout StrainsDietary energy restriction does not inhibit pancreatic carcinogenesis by N-nitrosobis-2-(oxopropyl)amine in the Syrian hamsterComparison of agricultural injuries reported in the media and census of fatal occupational injuries
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P50
description
hulumtuese
@sq
onderzoeker
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researcher
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հետազոտող
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name
Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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type
label
Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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prefLabel
Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
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Ellen G. Duysen
@sl
P106
P1153
6602514170
P21
P31
P496
0000-0002-0128-9032