Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

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Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

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2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

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name

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@en

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@nl

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Item

label

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@en

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@nl

prefLabel

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@en

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@nl

P1476

Endosomal acidification inhibitors for the treatment of BRAF mutant tumors.

@en

P2093

Lluís Espinosa

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P2860

Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.

KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor

Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes.

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.

ERK mutations confer resistance to mitogen-activated protein kinase pathway inhibitors.

A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer.

Combination of RAF and MEK inhibition for the treatment of BRAF-mutated melanoma: feedback is not encouraged.

P304

e1062073

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P31

scholarly article

P356

10.1080/23723556.2015.1062073

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P433

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P478

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P577

2015-11-18T00:00:00Z

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P698

27308590

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P932

4905373

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