In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases.
about
Computational approaches in target identification and drug discoveryAdvancements in therapeutically targeting orphan GPCRsA computational approach to evaluate the androgenic affinity of iprodione, procymidone, vinclozolin and their metabolitesDrug design for ever, from hype to hopeDecoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonistThe G Protein-Coupled Receptor GPR17: Overview and Update.Distant homology modeling of LCAT and its validation through in silico targeting and in vitro and in vivo assaysHunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain.Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury.Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.In silico studies in drug research against neurodegenerative diseases.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Identifying ligands at orphan GPCRs: current status using structure-based approaches.New winds in GPCR-based drug discovery.Present and future approaches to screening of G-protein-coupled receptors.Identification of small molecules uncoupling the Notch::Jagged interaction through an integrated high-throughput screening.Computer aided drug design and its application to the development of potential drugs for neurodegenerative disorders.Modeling and Deorphanization of Orphan GPCRs.GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury.
P2860
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P2860
In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
In silico identification of ne ...... or neurodegenerative diseases.
@en
In silico identification of ne ...... or neurodegenerative diseases.
@nl
type
label
In silico identification of ne ...... or neurodegenerative diseases.
@en
In silico identification of ne ...... or neurodegenerative diseases.
@nl
prefLabel
In silico identification of ne ...... or neurodegenerative diseases.
@en
In silico identification of ne ...... or neurodegenerative diseases.
@nl
P2093
P2860
P50
P1476
In silico identification of ne ...... or neurodegenerative diseases.
@en
P2093
Chiara Parravicini
Cristina Sensi
Ivano Eberini
Simona Daniele
P2860
P2888
P304
P356
10.1007/S10822-011-9455-8
P577
2011-07-09T00:00:00Z
P5875
P6179
1032609561