Single-copy chromosomal integration systems for Francisella tularensis
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Identification of small RNAs in Francisella tularensisFeoB-mediated uptake of iron by Francisella tularensisFipB, an essential virulence factor of Francisella tularensis subsp. tularensis, has dual roles in disulfide bond formation.Construction of mobilizable mini-Tn7 vectors for bioluminescent detection of gram-negative bacteria and single-copy promoter lux reporter analysis.Construction of a broad-host-range Tn7-based vector for single-copy P(BAD)-controlled gene expression in gram-negative bacteria.Requirement of the CXXC motif of novel Francisella infectivity potentiator protein B FipB, and FipA in virulence of F. tularensis subsp. tularensis.Identification and characterization of novel and potent transcription promoters of Francisella tularensis.FTT0831c/FTL_0325 contributes to Francisella tularensis cell division, maintenance of cell shape, and structural integrity.IglC and PdpA are important for promoting Francisella invasion and intracellular growth in epithelial cellsStable, site-specific fluorescent tagging constructs optimized for burkholderia species.Identification of a novel small RNA modulating Francisella tularensis pathogenicity.Importance of branched-chain amino acid utilization in Francisella intracellular adaptationRegulation of francisella tularensis virulence.Extragenic suppressor mutations in ΔripA disrupt stability and function of LpxA.A method for functional trans-complementation of intracellular Francisella tularensis.Revisiting the Gram-negative lipoprotein paradigm.Identifying Francisella tularensis genes required for growth in host cells.Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protectionGenetic engineering of Francisella tularensis LVS for use as a novel live vaccine platform against Pseudomonas aeruginosa infections.The Francisella tularensis FabI enoyl-acyl carrier protein reductase gene is essential to bacterial viability and is expressed during infection.Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune responseIglE is an outer membrane-associated lipoprotein essential for intracellular survival and murine virulence of type A Francisella tularensisWorking toward the future: insights into Francisella tularensis pathogenesis and vaccine development.TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain.Genetic manipulation of francisella tularensis.New applications for phage integrases.Asparagine assimilation is critical for intracellular replication and dissemination of Francisella.TetR-based gene regulation systems for Francisella tularensis.Nature of allosteric inhibition in glutamate racemase: discovery and characterization of a cryptic inhibitory pocket using atomistic MD simulations and pKa calculations.In silico optimization of a fragment-based hit yields biologically active, high-efficiency inhibitors for glutamate racemase.Exploiting a natural auxotrophy for genetic selection.Flooding enzymes: quantifying the contributions of interstitial water and cavity shape to ligand binding using extended linear response free energy calculations.Synthetic promoters functional in Francisella novicida and Escherichia coli.Chromosomal complementation using Tn7 transposon vectors in EnterobacteriaceaeCharacterization of stable, constitutively expressed, chromosomal green and red fluorescent transcriptional fusions in the select agent bacterium, Francisella tularensis Schu S4 and the surrogate type B live vaccine strain (LVS).Development of a novel Francisella tularensis Live Vaccine Strain expressing ovalbumin provides insight into antigen-specific CD8+ T cell responses.A Single Mechanosensitive Channel Protects Francisella tularensis subsp. holarctica from Hypoosmotic Shock and Promotes Survival in the Aquatic Environment.Construction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species.Structural and functional studies of the metalloregulator Fur identify a promoter-binding mechanism and its role in virulence
P2860
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P2860
Single-copy chromosomal integration systems for Francisella tularensis
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Single-copy chromosomal integration systems for Francisella tularensis
@en
Single-copy chromosomal integration systems for Francisella tularensis
@nl
type
label
Single-copy chromosomal integration systems for Francisella tularensis
@en
Single-copy chromosomal integration systems for Francisella tularensis
@nl
prefLabel
Single-copy chromosomal integration systems for Francisella tularensis
@en
Single-copy chromosomal integration systems for Francisella tularensis
@nl
P2093
P2860
P356
P1433
P1476
Single-copy chromosomal integration systems for Francisella tularensis
@en
P2093
Claudia R Molins-Schneekloth
Eric D LoVullo
Herbert P Schweizer
Martin S Pavelka
P2860
P304
P356
10.1099/MIC.0.022491-0
P577
2009-04-01T00:00:00Z