Gefitinib induces myeloid differentiation of acute myeloid leukemia.
about
A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancersSignal transduction inhibitors in treatment of myelodysplastic syndromesDiscovering hidden connections among diseases, genes and drugs based on microarray expression profiles with negative-term filteringRadotinib Induces Apoptosis of CD11b+ Cells Differentiated from Acute Myeloid Leukemia CellsDifferentiation therapy of leukemia: 3 decades of development.Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.Proteomic and genetic approaches identify Syk as an AML target.SYK regulates mTOR signaling in AML.What are the endpoints of therapy for acute leukemias? Old definitions and new challenges.Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection.Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cellsDasatinib inhibits the growth of molecularly heterogeneous myeloid leukemias.MEK/ERK dependent activation of STAT1 mediates dasatinib-induced differentiation of acute myeloid leukemia.Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.A phase II study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemiaKnockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia CellsVandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.Genetic and proteomic approaches to identify cancer drug targets.New sources of drugs for hematologic malignanciesGefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling.Erlotinib antagonizes ABC transporters in acute myeloid leukemia.Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemiaHOXA9 is required for survival in human MLL-rearranged acute leukemias.Genomic approaches to small molecule discovery.EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cellsIs there a role for differentiating therapy in non-APL AML?Systems biology visualization tools for drug target discovery.Conserved molecular mechanisms underlying the effects of small molecule xenobiotic chemotherapeutics on cells.Drug-induced pyoderma gangrenosum: a model to understand the pathogenesis of pyoderma gangrenosum.Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia.Epidermal growth factor receptor expression in acute myelogenous leukaemia is associated with clinical prognosis.Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia.In vitro evaluation of clinical activity and toxicity of anticancer drugs using tumor cells from patients and cells representing normal tissues.Identification of new possible targets for leukemia treatment by kinase activity profiling.Guanosine 5'-triphosphate induces differentiation-dependent apoptosis in human leukemia U937 and KG1 cells.Gefitinib potentiates myeloid cell differentiation by ATRAErlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells.Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia.Robust in vivo differentiation of t(8;21)-positive acute myeloid leukemia blasts to neutrophilic granulocytes induced by treatment with dasatinib.
P2860
Q21999537-6630564B-8466-46F1-BF6F-8313E4DD0B9DQ26829903-10C7F733-7135-43D9-BA8D-1FAAE3FC516AQ28539530-F5816EED-1FA8-46A4-AF16-CAE9F6C40092Q28548235-F76EA1C5-E600-4983-84B9-C0781FCCC26DQ33409795-3C204F09-D915-41D2-939E-D3DB30089460Q33526746-C4A435A8-C28F-48D6-AACE-3B4DBFEF2892Q33577098-E75FB388-87D9-496C-9FEA-EF7BF2E84460Q33641643-52222400-34BE-46DD-9639-94C3B26C04F6Q33775647-80F9ECDD-D75C-4C15-9469-F4A5B907941DQ34069315-14C00479-3A91-4668-A09C-794AE4EA6B2CQ34117127-71DE7B39-512D-4C4E-9414-2326769A40D9Q34335004-9D33362D-AB03-4C20-809E-0811968FEC11Q34794431-74CD18E0-8D76-43AB-BD89-5E3F3CE05545Q35030829-D5152F09-6747-4AAE-A0F1-CA8E59F4EB79Q35093305-93E920D8-8CAE-4EB4-BD86-680E1B852B2DQ35536200-4B6EEDA8-CA9D-4E9C-909A-439C322D12C0Q35569079-491DF13F-7136-423B-A7E2-5F67774B29D3Q35683353-E024947D-6FE7-4D5A-BB64-0ECA2C67C9B3Q35979113-5E098CAB-DCB4-419B-A494-10786F02986AQ36291109-2DDB7833-5F67-4E32-AC1A-56DF1FA065E1Q36426524-02293980-A954-427C-9A3E-3ADFB82ADA03Q36882696-E05E3FBB-0BFF-4948-AE59-2F114B284EC6Q37123272-579042A1-07B4-480A-A7F0-32B3BBF4AC9DQ37129652-EA411D89-3407-4FC2-8895-12D3FF6E379EQ37406963-2AC44AC6-919B-4996-9CED-E9EC11E04D64Q37420045-E2FF8761-46B4-44EF-931D-A5E408CA68FDQ37815790-C102C311-51C6-4692-99B3-245DAA832677Q38028544-E9E7883E-127B-4D83-A0EC-33BDD3A808A6Q38719813-E33A1CB0-F0B5-4A65-BD5B-BEC6E4B366AFQ39013880-C0477250-E725-4CC4-897C-DE3A2C6BB208Q39255686-FEE76FBE-2C77-46D2-99D4-0F8E00AF28BDQ39335663-5E0E3F64-A095-40F2-BE5F-259C40E0EFC5Q39439229-79B7D935-3E7A-45A4-AC75-6FDDA08AC3CDQ39460944-EBFC4D37-C99A-4D8A-8ECA-D6BD17B0F7B3Q39623499-D6A91C8C-9349-4EFF-8894-3A1450CA653FQ40241248-A87D5703-F918-42FB-9521-879FA99C9946Q41181298-56BAAD06-A119-483C-A218-9D6599BBA93EQ42362038-5EFBD674-1AA7-4264-AB61-D5C2A0E26C9BQ42383776-DF3A4A65-5C7C-4DE7-BF7D-D078D0E1A38BQ42919966-DA894C99-3EE8-4CD7-A357-D5B7E2E4FD92
P2860
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@en
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@nl
type
label
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@en
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@nl
prefLabel
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@en
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@nl
P2093
P2860
P1433
P1476
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
@en
P2093
Daniel J Deangelo
Jenny S Wong
Kenneth N Ross
Steven M Corsello
Todd R Golub
P2860
P304
P356
10.1182/BLOOD-2005-02-0488
P407
P577
2005-07-05T00:00:00Z