about
Analysis of mutations causing biotinidase deficiencyDevelopment and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorderPristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2.Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin.Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activityNeurological deficits in mice with profound biotinidase deficiency are associated with demylination and axonal degenerationRole of telomerase in anticancer activity of pristimerin in prostate cancer cells.TNF-alpha gene therapy with myeloid progenitor cells lacks the toxicities of systemic TNF-alpha therapy.Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane).Curcumin, a compound with anti-inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells.IL-4 upregulates IL-1-induced chemokine gene expression in bone marrow stromal cells by enhancing NF-kB activation.Induction of chemokine mRNA in bone marrow stromal cells: modulation by TGF-beta 1 and IL-4.Candidate disorders for gene therapy: newborn screening facilitates ascertainment of presymptomatic individuals.Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder.Characterization and functional analysis of cellular immunity in mice with biotinidase deficiencyA rapid and sensitive approach to mutation detection using real-time polymerase chain reaction and melting curve analyses, using BRCA1 as an exampleEnhanced assessment of allogeneic bone marrow transplant engraftment using automated fluorescent-based typingCurcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cellsMutations in the von Hippel-Lindau (VHL) gene refine differential diagnostic criteria in renal cell carcinomaThree dimensional structure of human biotinidase: computer modeling and functional correlationsBiotinidase deficiency mimicking neuromyelitis optica: Initially exhibiting symptoms in adulthood
P50
Q28285581-CFA3FD92-FF81-4608-AD9E-DCDEE6A31435Q28593216-138513B7-8454-466C-9454-33537C424FECQ33636979-F4579D39-FBA5-451B-AB01-615BB5AC33D7Q34069749-2B90BD5A-B496-497E-AA99-B28BF3CCF52AQ34120378-186AA1AD-634E-473C-A3C7-6D9656E7CA2AQ35794329-1C9D3A9C-E088-4C05-BE1C-9E0859C56EBFQ36622696-CB6289BB-54ED-4DC2-8BBE-A83E30122361Q37675615-1DEDBB99-9150-454F-B760-7CB84D657BA9Q38844869-E4850ADD-14FA-487E-852B-12AEFBD256E6Q40940218-21A5A2BF-4402-47DD-BB38-1F04B22CB39CQ41012754-C28EB91F-0AEC-498E-8B8A-C4A8A66EE85CQ41113233-4B8DEDFD-8D39-40A4-B3BD-1436FBB358B6Q41242974-98759804-6A3A-456F-B4DE-04C4C0F385DCQ41338528-162BFEED-BFE5-43F5-85CA-FEA597250D7FQ45875376-9C2C0C88-8C6B-4C70-ADA6-FFB72BAE86FDQ46313104-D6918912-35C4-4F74-9994-7F1996835A26Q58966944-0946BCF3-1694-4FA9-8B74-1165432A2BD8Q73160634-96B6D5B3-38BA-4F0C-977C-9347F0CA5372Q73372647-F7AB4399-7FD2-47E9-BE31-58BA0783B8C3Q74080109-1718D5BC-C211-47B7-BBD2-A40315DEF88FQ77985962-C9F4018D-494F-4E62-BB17-4A4331DD0461Q80608083-A78F2613-8327-4451-8B69-A8D1CC4C4880Q85643329-AA1411A2-D8DA-4883-B5E1-813AF721E041
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Kirit Pindolia
@ast
Kirit Pindolia
@en
Kirit Pindolia
@es
Kirit Pindolia
@nl
Kirit Pindolia
@sl
type
label
Kirit Pindolia
@ast
Kirit Pindolia
@en
Kirit Pindolia
@es
Kirit Pindolia
@nl
Kirit Pindolia
@sl
prefLabel
Kirit Pindolia
@ast
Kirit Pindolia
@en
Kirit Pindolia
@es
Kirit Pindolia
@nl
Kirit Pindolia
@sl
P106
P31
P4012
P496
0000-0001-5284-9303