Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.
about
PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.Non-Invasive Intravital Imaging of siRNA-Mediated Mutant Keratin Gene Repression in Skin.Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy.CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting.Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.High-Throughput Screening for Drugs that Modulate Intermediate Filament ProteinsAllele-specific silencing of EEC p63 mutant R304W restores p63 transcriptional activity.Corneal dystrophies and genetics in the International Committee for Classification of Corneal Dystrophies era: a review.ASPsiRNA: A Resource of ASP-siRNAs Having Therapeutic Potential for Human Genetic Disorders and Algorithm for Prediction of Their Inhibitory Efficacy.Correction of Mutant p63 in EEC Syndrome Using siRNA Mediated Allele-Specific Silencing Restores Defective Stem Cell Function.Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders.
P2860
Q35678892-8702A999-0A55-4D3A-8C4A-45B6BA61E240Q35689975-DFB90F68-B0E7-48D3-BC0B-B3F39F9F8694Q36440529-42DEE3A8-6D8E-4187-92BD-DE88F532846AQ36442476-7EBF02B3-E5B4-42C1-AEA1-9429B548386FQ36608872-7DD70A63-18D3-4DAA-AA86-9681A015F165Q36865175-788BC566-6C68-40AB-98A7-454B36F835B6Q37030292-D975C497-1ADD-4796-A226-A319EE548328Q38179067-E02BF382-4177-44DD-A04D-D31DC232982EQ41385002-438645EB-202C-4609-B811-34DA4F579568Q45883315-BF891EA9-BF27-448C-B45C-FC928BA0A216Q46663082-70B769D5-593B-4631-BED6-8C257EBDC128
P2860
Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@en
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@nl
type
label
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@en
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@nl
prefLabel
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@en
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@nl
P2093
P2860
P50
P356
P1476
Allele-specific siRNA silencin ...... epithelial corneal dystrophy.
@en
P2093
C B Tara Moore
Edwin H A Allen
Frances J D Smith
Haihui Liao
Jonathan E Moore
P2860
P304
P356
10.1167/IOVS.12-10528
P407
P577
2013-01-17T00:00:00Z