G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. - Wikidata - awgldk - TriplyDB

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.

http://www.wikidata.org/entity/Q42785249

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Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation Control of bacterial nitrate assimilation by stabilization of G-quadruplex DNA The C-kit receptor-mediated signal transduction and tumor-related diseases Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies.Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands.Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.Structural and affinity analyses of g-quadruplex DNA aptamers for camptothecin derivatives Targeting a c-MYC G-quadruplex DNA with a fragment library.New insights into transcription fidelity: thermal stability of non-canonical structures in template DNA regulates transcriptional arrest, pause, and slippage.Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.A Personal History of Quadruplex-Small Molecule Targeting.Investigation of a Quadruplex-Forming Repeat Sequence Highly Enriched in Xanthomonas and Nostoc sp.Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models.Extended molecular dynamics of a c-kit promoter quadruplex.Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands.Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control.A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals The application of DNA and RNA G-quadruplexes to therapeutic medicines.Fluorescent probes for G-quadruplex structures.G-quadruplex structures in the human genome as novel therapeutic targets.G-quadruplex interacting small molecules and drugs: from bench toward bedside.Site-specific control of N7-metal coordination in DNA by a fluorescent purine derivative.Synthesis and Evaluation of Quinazolone Derivatives as a New Class of c-KIT G-Quadruplex Binding Ligands.Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains.Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes.Flexibility and structural conservation in a c-KIT G-quadruplex.A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif.[Ru(bpy)2dppz-idzo]2+: a colorimetric molecular "light switch" and powerful stabilizer for G-quadruplex DNA.Conformational profiling of a G-rich sequence within the c-KIT promoter.Spectroscopic and biological studies of phenanthroline compounds: selective recognition of gene-promoter G-quadruplex DNAs preferred over duplex DNA.Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders.Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex.Platinum(II) clovers targeting G-quadruplexes and their anticancer activities.Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids Fluorescent Dansyl-Guanosine Conjugates that Bindc-MYCPromoter G-Quadruplex and Downregulatec-MYCExpression

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P2860

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.

http://www.wikidata.org/entity/Q42785249

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@en

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@nl

type

label

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@en

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@nl

prefLabel

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@en

G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@nl

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Journal of the American Chemical Society

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G-quadruplex-binding benzo[a]p ...... human gastric carcinoma cells.

@en

P2093

Ashok R Venkitaraman

http://www.w3.org/2001/XMLSchema#string

David Alves

http://www.w3.org/2001/XMLSchema#string

Deborah A Sanders

http://www.w3.org/2001/XMLSchema#string

Grahame J McKenzie

http://www.w3.org/2001/XMLSchema#string

Jyotirmayee Dash

http://www.w3.org/2001/XMLSchema#string

Keith I E McLuckie

http://www.w3.org/2001/XMLSchema#string

Shankar Balasubramanian

http://www.w3.org/2001/XMLSchema#string

Zoë A E Waller

http://www.w3.org/2001/XMLSchema#string

P2860

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

Molecular correlates of imatinib resistance in gastrointestinal stromal tumors.

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation

Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults

c-Kit--a hematopoietic cell essential receptor tyrosine kinase

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

Bioluminescent assays for high-throughput screening.

Establishment of an in vitro test system to evaluate the down-regulatory activities of natural products on IL-4.

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

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2658-2663

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scholarly article

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10.1021/JA109474C

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8

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133

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Raphaël Rodriguez

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2011-02-04T00:00:00Z

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49810880

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21294544

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3128987

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