about
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel diseaseGenome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility lociGenome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controlsGenome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A regionNegligible impact of rare autoimmune-locus coding-region variants on missing heritabilityRare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation.Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genesGene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis.T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studiesHuman SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements.Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunityGenome-wide association studies and Crohn's disease.Predicting the course of IBD: light at the end of the tunnel?Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype.Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory PolyarthritisExploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.Pneumocystis jiroveci pneumonia and pneumomediastinum in an anti-TNFalpha naive patient with ulcerative colitis.Genome-wide association studies in Crohn's disease: Past, present and future.Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel diseasePRedicting Outcomes For Crohn's dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trialAdjustment for index event bias in genome-wide association studies of subsequent eventsGenetic association between NLRP3 variants and Crohn's disease does not replicate in a large UK panelSafety of the colonoscope magnetic imaging device (ScopeGuide) in patients with implantable cardiac devicesNovel developments in Crohn's diseaseResolving mechanisms of immune-mediated disease in primary CD4 T cellsThe Firre locus produces a trans-acting RNA molecule that functions in hematopoiesisA blood-based prognostic biomarker in IBD
P50
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P50
description
hulumtues
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researcher
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հետազոտող
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name
James Lee
@ast
James Lee
@en
James Lee
@es
James Lee
@nl
James Lee
@sl
Джеймс Ли
@ru
type
label
James Lee
@ast
James Lee
@en
James Lee
@es
James Lee
@nl
James Lee
@sl
Джеймс Ли
@ru
prefLabel
James Lee
@ast
James Lee
@en
James Lee
@es
James Lee
@nl
James Lee
@sl
Джеймс Ли
@ru
P106
P1153
55877297541
55877297545
P21
P31
P496
0000-0001-5711-9385