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Effects of Brassicaceae Isothiocyanates on Prostate CancerActivation of the DNA Damage Response by RNA VirusesWee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomasWee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumptionTranscriptional regulation is a major controller of cell cycle transition dynamicsJNK-mediated phosphorylation of Cdc25C regulates cell cycle entry and G(2)/M DNA damage checkpoint.Functional characterization of the diatom cyclin-dependent kinase A2 as a mitotic regulator reveals plant-like properties in a non-green lineageThe Arabidopsis thaliana checkpoint kinase WEE1 protects against premature vascular differentiation during replication stress.Regulation of the G2/M phase of the cell cycle by sperm associated antigen 8 (SPAG8) protein.An ultra-high throughput cell-based screen for wee1 degradation inhibitorsMammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.Genome-wide analysis of the diatom cell cycle unveils a novel type of cyclins involved in environmental signaling.Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo.Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo.The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase.The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forksResveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.A PREVIOUSLY UNKNOWN UNIQUE CHALLENGE FOR INHIBITORS OF SYK ATP-BINDING SITE: ROLE OF SYK AS A CELL CYCLE CHECKPOINT REGULATORS100A8/A9 (calprotectin) negatively regulates G2/M cell cycle progression and growth of squamous cell carcinoma.Identification of a Wee1-like kinase gene essential for procyclic Trypanosoma brucei survival.Morphogenesis and the cell cycleRole for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extractsRoles of Greatwall kinase in the regulation of cdc25 phosphatase.Classic "broken cell" techniques and newer live cell methods for cell cycle assessmentThe Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle ProgressionQuantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer.The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATMGenome-wide annotation, expression profiling, and protein interaction studies of the core cell-cycle genes in Phalaenopsis aphrodite.Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1.The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites.Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo.Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.Cross-talk between the circadian clock and the cell cycle in cancer.Expression and clinical significance of Wee1 in colorectal cancer.MicroRNA-219-5p Inhibits Morphine-Induced Apoptosis by Targeting Key Cell Cycle Regulator WEE1.Bistability of mitotic entry and exit switches during open mitosis in mammalian cells.The cell cycle checkpoint inhibitors in the treatment of leukemias.Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication.Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cdc25 and Wee1: analogous opposites?
@en
Cdc25 and Wee1: analogous opposites?
@nl
type
label
Cdc25 and Wee1: analogous opposites?
@en
Cdc25 and Wee1: analogous opposites?
@nl
prefLabel
Cdc25 and Wee1: analogous opposites?
@en
Cdc25 and Wee1: analogous opposites?
@nl
P2860
P356
P1433
P1476
Cdc25 and Wee1: analogous opposites?
@en
P2093
Jennifer A Perry
Sally Kornbluth
P2860
P2888
P356
10.1186/1747-1028-2-12
P577
2007-05-04T00:00:00Z
P5875
P6179
1023865212