The read-across hypothesis and environmental risk assessment of pharmaceuticals.
about
From the exposome to mechanistic understanding of chemical-induced adverse effectsSimilar anxiolytic effects of agonists targeting serotonin 5-HT1A or cannabinoid CB receptors on zebrafish behavior in novel environmentsAre pharmaceuticals with evolutionary conserved molecular drug targets more potent to cause toxic effects in non-target organisms?Quantitative cross-species extrapolation between humans and fish: the case of the anti-depressant fluoxetineMedicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems.Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms.The effects of antidepressants appear to be rapid and at environmentally relevant concentrations.Assessing variation in the potential susceptibility of fish to pharmaceuticals, considering evolutionary differences in their physiology and ecologyComparative pharmacology and toxicology of pharmaceuticals in the environment: diphenhydramine protection of diazinon toxicity in Danio rerio but not Daphnia magnaHuman pharmaceuticals in the marine environment: Focus on exposure and biological effects in animal species.The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment.Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish.Testing the "read-across hypothesis" by investigating the effects of ibuprofen on fishPharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance.Pharmaceuticals in the environment: expected and unexpected effects on aquatic fauna.Determining potential adverse effects in marine fish exposed to pharmaceuticals and personal care products with the fish plasma model and whole-body tissue concentrations.Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.Practical approaches to adverse outcome pathway development and weight-of-evidence evaluation as illustrated by ecotoxicological case studies.Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities.20 Years of fish immunotoxicology - what we know and where we are.Bioaccumulation of human pharmaceuticals in fish across habitats of a tidally influenced urban bayou.Occurrence of 25 pharmaceuticals in Taihu Lake and their removal from two urban drinking water treatment plants and a constructed wetland.A rational approach to selecting and ranking some pharmaceuticals of concern for the aquatic environment and their relative importance compared with other chemicals.Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, in fathead minnows.Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large-scale mammalian pharmacological dataset.A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: evidence for passive and facilitated transport.Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects.An in vitro method for determining the bioaccessibility of pharmaceuticals in wildlife.Effect of bioconcentration and trophic transfer on realized exposure to oxazepam in 2 predators, the dragonfly larvae (Aeshna grandis) and the Eurasian perch (Perca fluviatilis).Fast-Target Analysis and Hourly Variation of 60 Pharmaceuticals in Wastewater Using UPLC-High Resolution Mass Spectrometry.In response: governmental perspective.Developing analytical approaches to explore the connection between endocrine-active pharmaceuticals in water to effects in fish.A review of the pharmaceutical exposome in aquatic fauna.Transcriptional Responses Reveal Similarities Between Preclinical Rat Liver Testing Systems.Urbanization, environment and pharmaceuticals: advancing comparative physiology, pharmacology and toxicology
P2860
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P2860
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@en
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@nl
type
label
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@en
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@nl
prefLabel
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@en
The read-across hypothesis and environmental risk assessment of pharmaceuticals.
@nl
P2093
P2860
P356
P1476
The read-across hypothesis and environmental risk assessment of pharmaceuticals
@en
P2093
Alpa Patel
Grace H Panter
John P Sumpter
Mariann Rand-Weaver
P2860
P304
11384-11395
P356
10.1021/ES402065A
P407
P577
2013-09-30T00:00:00Z