A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.
about
New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progressionMultiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activitySpatial regulation of RhoC activity defines protrusion formation in migrating cellsRational design and characterization of a Rac GTPase-specific small molecule inhibitorIntegrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.Proteomic analyses of the Xiphophorus Gordon-Kosswig melanoma model.Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensionsToward understanding RhoGTPase specificity: structure, function and local activation.Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growthRhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblastsIncreased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts.HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinomaGenetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment.Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification.Hyaluronic acid-serum hydrogels rapidly restore metabolism of encapsulated stem cells and promote engraftment.Sdc1 negatively modulates carcinoma cell motility and invasion.ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma.Arg188 drives RhoC membrane binding.Induction of small G protein RhoB by non-genotoxic stress inhibits apoptosis and activates NF-κB.PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling.Loss of cell-cell contacts induces NF-kappaB via RhoA-mediated activation of protein kinase D1Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis.MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration.A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells.RhoB: Team Oncogene or Team Tumor Suppressor?Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models.RhoC
P2860
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P2860
A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
A novel strategy for specifica ...... TPase activity in tumor cells.
@en
A novel strategy for specifica ...... TPase activity in tumor cells.
@nl
type
label
A novel strategy for specifica ...... TPase activity in tumor cells.
@en
A novel strategy for specifica ...... TPase activity in tumor cells.
@nl
prefLabel
A novel strategy for specifica ...... TPase activity in tumor cells.
@en
A novel strategy for specifica ...... TPase activity in tumor cells.
@nl
P2093
P2860
P356
P1476
A novel strategy for specifica ...... TPase activity in tumor cells.
@en
P2093
P2860
P304
44617-44625
P356
10.1074/JBC.M308929200
P407
P577
2003-08-25T00:00:00Z