Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse.
about
A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisisHuman COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation.Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta.The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2.Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene.Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).Different cis-regulatory DNA elements mediate developmental stage- and tissue-specific expression of the human COL2A1 gene in transgenic mice.Molecular cloning, sequencing, and tissue and developmental expression of mouse cartilage oligomeric matrix protein (COMP).The non-collagenous dentin matrix proteins are involved in dentinogenesis imperfecta type II (DGI-II).Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice.
P2860
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P2860
Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Structural analysis of the reg ...... ences between human and mouse.
@en
Structural analysis of the reg ...... ences between human and mouse.
@nl
type
label
Structural analysis of the reg ...... ences between human and mouse.
@en
Structural analysis of the reg ...... ences between human and mouse.
@nl
prefLabel
Structural analysis of the reg ...... ences between human and mouse.
@en
Structural analysis of the reg ...... ences between human and mouse.
@nl
P2093
P2860
P356
P1433
P1476
Structural analysis of the reg ...... ences between human and mouse.
@en
P2093
Ala-Kokko L
Metsäranta M
Peltonen L
Syvänen AC
P2860
P304
P356
10.1042/BJ2850287
P407
P478
285 ( Pt 1)
P577
1992-07-01T00:00:00Z