A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents.
about
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activityA new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosisp53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiationA comprehensive pathway map of epidermal growth factor receptor signalingp38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the StoryCancer prevention with promising natural products: mechanisms of action and molecular targetsBalance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLCProlonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 inductionJun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.Cisplatin induces cytotoxicity through the mitogen-activated protein kinase pathways and activating transcription factor 3.ROS, stress-activated kinases and stress signaling in cancer.Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.Helicobacter pylori bacteria alter the p53 stress response via ERK-HDM2 pathway.Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK.Role of stress-activated MAP kinase P38 in cisplatin- and DTT-induced apoptosis of the esophageal carcinoma cell line Eca109.ATM and ATR: sensing DNA damage.Mechanism of p38 MAP kinase activation in vivo.Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severityTargeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells.Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cellsp53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathwaysCCR5 expression influences the progression of human breast cancer in a p53-dependent mannerLocation, location, location: altered transcription factor trafficking in neurodegeneration.Kaposi's sarcoma-associated herpesvirus K-cyclin interacts with Cdk9 and stimulates Cdk9-mediated phosphorylation of p53 tumor suppressorThe mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cellsMegakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction.Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cellsERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma.A phylogenetically conserved DNA damage response resets the circadian clock.Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53.BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines.H2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase.Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity.A role for p38 MAPK in head and neck cancer cell growth and tumor-induced angiogenesis and lymphangiogenesis.Role of MAPK p38 in the cellular responses to pore-forming toxins.Ionizing radiation-induced responses in human cells with differing TP53 status.Induction of Activating Transcription Factor 3 Is Associated with Cisplatin Responsiveness in Non-Small Cell Lung Carcinoma Cells.Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation.
P2860
Q21284181-8A000E66-44F9-4545-9029-2DE7FA9A471CQ24300728-CFE8ED75-C782-4119-A61A-AA109786566EQ24596239-9BF0EE12-EFEB-4113-BC3C-02AC599C4CA0Q24672490-2416AA54-2CFC-4F65-8520-3A1E65B5F887Q26742078-E51BDFB0-3CA6-47C1-B8D8-6251FD4C7466Q27006530-2DC65A39-3A27-4857-A508-923E082768EEQ28478252-DE64EA65-4752-4D17-9152-69DD2C554951Q30505355-802283AA-FADF-422B-9575-E571F178194BQ33967914-995BD018-214E-44CB-BDCE-20A01CE62F39Q34009832-D9F7C6A5-D3A3-4450-BD3C-C0CF664CE386Q34625850-7FF037A8-335F-42BA-8DC4-9558F25CDA18Q34789354-AEE26723-15AE-49DB-87A9-867C74407968Q35176360-6B60F363-D273-4379-9E23-DE23D37F65A6Q35193348-C939B2AC-2B13-4AC1-BED6-25BD73CB598AQ35435309-0B8A5FDB-726C-466D-BB1F-DA98E5EBA638Q35625983-5B65DEA5-2468-47C1-BD4B-000CA072625DQ35967224-9A9229DC-D9E9-443C-99B1-6ACA62B6493CQ35969173-83CB3D6B-F72E-480F-84AC-A335158A6B9AQ36062088-3773EB75-6F0F-4127-A5BD-962023235519Q36149227-D44E504D-DF4C-4690-9582-FAA10E984219Q36231932-EF9CABC7-351D-46D9-A7CD-654FE33FCBA5Q36371823-70D6979C-BE30-4E81-BC36-48C9C6306D2FQ36417568-236FA36F-8752-4C74-9A7D-E0FBD8AD84D6Q36423989-73E70336-2F3B-416F-906A-95350D183B45Q36661071-67F30FE2-B0D4-4403-B0B8-157B9EF7F65EQ36778744-4698065A-E0EF-41A9-BC2E-9837520FA3F0Q36863596-81F5FF30-4925-47C0-940B-4971A010F295Q36879241-4DC63E5C-D0EF-4701-8F5D-868FFCF62644Q36932724-E640A6AE-1B64-4D3D-A87B-F5BBB43B5676Q36949142-04834B00-9F40-4F83-B87B-C7506B2D09CFQ37142574-13A5F5A9-039B-415A-8B76-CCA67D82E01FQ37152889-24D238BD-AAEE-4062-A071-3E756904E8B3Q37355092-01FA7307-6B0D-472C-BCAF-9E23C4ED8EEDQ37398303-D3FF1540-F5B0-4095-969C-E4F52D9F1705Q37419174-1CACE688-C1C7-4E36-82A7-E38EC4338FB0Q37625140-2A48D12B-4555-476A-9598-1AD8970A605AQ37769785-D8CAB8CE-3962-434A-95A6-97CEF8FB2938Q38162722-4B4840AD-1EFF-4823-9E46-F77D29F9B01AQ38744268-42A61F8C-0B32-4400-97E0-C9BEB2D0AA08Q38761819-6B9B0824-53D6-4970-B821-B397B1481768
P2860
A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@en
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@nl
type
label
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@en
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@nl
prefLabel
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@en
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@nl
P2093
P1433
P1476
A role for the p38 mitogen-aci ...... ss by chemotherapeutic agents.
@en
P2093
Gutkind JS
Sanchez-Prieto R
P304
P407
P577
2000-05-01T00:00:00Z