Cell cycle-specific association of E2F with the p130 E1A-binding protein.
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleAssociation of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition elementRaf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulationRoscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteinsInhibition of E2F-mediated transcription by p202E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycleIdentification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcriptionA unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiationInteraction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivationGenetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid systemRegulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinasesGenomic structure of the human retinoblastoma-related Rb2/p130 geneStructural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DPCyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylationDP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivoE2F activity is regulated by cell cycle-dependent changes in subcellular localizationFunctional interaction between DP-1 and p53Cyclin A expression is under negative transcriptional control during the cell cycleId2 specifically alters regulation of the cell cycle by tumor suppressor proteinsE2F-4 switches from p130 to p107 and pRB in response to cell cycle reentryIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionAssociation of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcriptionE2F-5, a new E2F family member that interacts with p130 in vivoIn vivo association of E2F and DP family proteinsmiR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130Deregulated E2F transcriptional activity in autonomously growing melanoma cellsMechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth.Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F functionDifferential activities of E2F family members: unique functions in regulating transcriptionTumor suppressors and cell-cycle proteins in lung cancerSubcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscleThe p53-dependent effects of macrophage migration inhibitory factor revealed by gene targetingA specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targetingp130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activityRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesIdentification of a novel E1A response element in the mouse c-fos promoter.c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry.Regulation of cellular genes in a chromosomal context by the retinoblastoma tumor suppressor proteinDual cyclin-binding domains are required for p107 to function as a kinase inhibitor.Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
P2860
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P2860
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@en
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@nl
type
label
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@en
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@nl
prefLabel
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@en
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@nl
P2093
P356
P1433
P1476
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
@en
P2093
P304
P356
10.1101/GAD.7.12A.2392
P577
1993-12-01T00:00:00Z