ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate
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Ethanol, Zn2+ and insulin interact as progression factors to enhance DNA synthesis synergistically in the presence of Ca2+ and other cell cycle initiators in fibroblastsSphingosine 1-phosphate signalling in mammalian cells.Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.Choline kinase alpha-Putting the ChoK-hold on tumor metabolism.Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways.Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.Placental mammalian target of rapamycin and related signaling pathways in an ovine model of intrauterine growth restrictionPlacenta growth factor induces invasion and activates p70 during rapamycin treatment in trophoblast cells.Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C.P2Y receptor-mediated inhibition of tumor necrosis factor alpha -stimulated stress-activated protein kinase activity in EAhy926 endothelial cells.Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling.Growth factor-like effects of placental alkaline phosphatase in human fetus and mouse embryo fibroblasts.CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway.Extracellular calcium stimulates DNA synthesis in synergism with zinc, insulin and insulin-like growth factor I in fibroblasts.Phosphocholine and sphingosine-1-phosphate synergistically stimulate DNA synthesis by a MAP kinase-dependent mechanism.Ethanol potentiates the stimulatory effects of insulin and phosphocholine on mitogenesis by a zinc-dependent and rapamycin-sensitive mechanism in fibroblasts and JB6 cells.Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine.Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor kappaB activation in tumour-necrosis-factor-alpha-treated immature acute-myeloid-leukaemia cells.Alkyl lysophospholipids inhibit phorbol ester-stimulated phospholipase D activity and DNA synthesis in fibroblasts.The possible mechanism of synergistic effects of ethanol, zinc and insulin on DNA synthesis in NIH 3T3 fibroblasts.Ethanolamine, but not phosphoethanolamine, potentiates the effects of insulin, phosphocholine, and ATP on DNA synthesis in NIH 3T3 cells--role of mitogen-activated protein-kinase-dependent and protein-kinase-independent mechanisms.Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.Bombesin and zinc enhance the synergistic mitogenic effects of insulin and phosphocholine by a MAP kinase-dependent mechanism in Swiss 3T3 cells.Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.Decreased activation of placental mTOR family members is associated with the induction of intrauterine growth restriction by secondhand smoke in the mouse.
P2860
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P2860
ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@en
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@nl
type
label
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@en
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@nl
prefLabel
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@en
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@nl
P2093
P2860
P356
P1476
ATP-dependent choline phosphat ...... te and sphingosine 1-phosphate
@en
P2093
P2860
P304
P356
10.1074/JBC.272.5.3064
P407
P577
1997-01-01T00:00:00Z