Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase.
about
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent mannerA proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK functionAssociation of MEK1 with p21ras.GMPPNP is dependent on B-Raf.The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21raszeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylationSorafenib cardiotoxicity increases mortality after myocardial infarction.Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinaseEnzymatic characteristics of the c-Raf-1 protein kinaseCardiovascular safety of VEGF-targeting therapies: current evidence and handling strategiesRaf-1 protein is required for growth factor-induced proliferation of hematopoietic cellsAn intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ.MEK-1 activates C-Raf through a Ras-independent mechanism.Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase.Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction.Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils.Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics.The ERK Cascade: Distinct Functions within Various Subcellular Organelles.Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells.Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway.Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists.Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein.Role of tyrosine kinase and protein kinase C in the steroidogenic actions of angiotensin II, alpha-melanocyte-stimulating hormone and corticotropin in the rat adrenal cortex.P(2Y) purinoceptor subtypes recruit different mek activators in astrocytes.
P2860
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P2860
Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@en
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@nl
type
label
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@en
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@nl
prefLabel
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@en
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@nl
P2093
P1476
Mitogen regulation of c-Raf-1 ...... tivated protein kinase-kinase.
@en
P2093
P304
16009-16019
P407
P577
1993-07-01T00:00:00Z