PAX6, paired domain influences sequence recognition by the homeodomain. - Wikidata - awgldk - TriplyDB

PAX6, paired domain influences sequence recognition by the homeodomain.

PAX6, paired domain influences sequence recognition by the homeodomain.

http://www.wikidata.org/entity/Q42809226

about

Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11 The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2 Isolation and expression of Pax6 and atonal homologues in the American horseshoe crab, Limulus polyphemus Cephalopod eye evolution was modulated by the acquisition of Pax-6 splicing variants Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.Targeted Exome Sequencing of Congenital Cataracts Related Genes: Broadening the Mutation Spectrum and Genotype-Phenotype Correlations in 27 Chinese Han Families.Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene.Concise review: hurdles in a successful example of limbal stem cell-based regenerative medicine.Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing.Genetic analysis of the Caenorhabditis elegans pax-6 locus: roles of paired domain-containing and nonpaired domain-containing isoforms.The homeodomain of Eyeless regulates cell growth and antagonizes the paired domain-dependent retinal differentiation function Macrophage/epithelium cross-talk regulates cell cycle progression and migration in pancreatic progenitors.Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens.Mutation analysis of PAX6 in inherited and sporadic aniridia from northeastern China Functional properties of natural human PAX6 and PAX6(5a) mutants Linkers in the structural biology of protein-protein interactions Relationship of Pax6 activity levels to the extent of eye development in the mouse, Mus musculus Dopamine systems in the forebrain.The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences.Mutant PAX6 downregulates prohormone convertase 2 expression in mouse islets.Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency.Pax6 interacts with SPARC and TGF-β in murine eyes.The proliferation and expansion of retinal stem cells require functional Pax6.Mutation analysis of PAX6 in a Chinese family and a patient with a presumed sporadic case of congenital aniridia.The effect of haplotype variation in the bovine PAX6 gene.A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye.PAX6Mutations May Be Associated with High Myopia Two Paired Box 6 mutations identified in Chinese patients with classic congenital aniridia and cataract

P2860

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P2860

PAX6, paired domain influences sequence recognition by the homeodomain.

http://www.wikidata.org/entity/Q42809226

description

2002 nî lūn-bûn

@nan

2002年の論文

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2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

@zh

2002年论文

@zh-cn

name

PAX6, paired domain influences sequence recognition by the homeodomain.

@en

PAX6, paired domain influences sequence recognition by the homeodomain.

@nl

type

label

PAX6, paired domain influences sequence recognition by the homeodomain.

@en

PAX6, paired domain influences sequence recognition by the homeodomain.

@nl

prefLabel

PAX6, paired domain influences sequence recognition by the homeodomain.

@en

PAX6, paired domain influences sequence recognition by the homeodomain.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

PAX6, paired domain influences sequence recognition by the homeodomain.

@en

P2093

Grady F Saunders

http://www.w3.org/2001/XMLSchema#string

Ivan P Gorlov

http://www.w3.org/2001/XMLSchema#string

Lian Y Chao

http://www.w3.org/2001/XMLSchema#string

Rajnikant Mishra

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Sanjaya Singh

http://www.w3.org/2001/XMLSchema#string

P2860

Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies

Modulation of PAX6 homeodomain function by the paired domain

Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

Pax 6: mastering eye morphogenesis and eye evolution

Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins

Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

Getting your Pax straight: Pax proteins in development and disease

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

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49488-49494

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scholarly article

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10.1074/JBC.M206478200

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51

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277

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2002-10-17T00:00:00Z

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12388550

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