SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. - Wikidata - awgldk - TriplyDB

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.

http://www.wikidata.org/entity/Q42810891

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Sphingolipids: a potential molecular approach to treat allergic inflammation Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide An overview of sphingolipid metabolism: from synthesis to breakdown Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate Evolving concepts in cancer therapy through targeting sphingolipid metabolism The compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolism Sphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progress Export of sphingosine-1-phosphate and cancer progression Sphingolipids in spinal cord injury Inhibition of Sphingosine Kinase by Bovine Viral Diarrhea Virus NS3 Is Crucial for Efficient Viral Replication and Cytopathogenesis Sphingosine kinase 1 is a reliable prognostic factor and a novel therapeutic target for uterine cervical cancer.Characterization of isoenzyme-selective inhibitors of human sphingosine kinases Cloning and characterization of rat sphingosine kinase 1 with an N-terminal extension Sphingosine kinase 1 Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors.Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney disease Determination of sphingosine kinase activity for cellular signaling studies.Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophages Dual inhibition of sphingosine kinase isoforms ablates TNF-induced drug resistance.An introduction to sphingolipid metabolism and analysis by new technologies Sphingosine kinase (SphK) 1 and SphK2 play equivalent roles in mediating insulin's mitogenic action Sphingosine kinase and sphingosine 1-phosphate in cardioprotection.Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2 Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.Multiple roles for sphingolipids in steroid hormone biosynthesis

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P2860

SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.

http://www.wikidata.org/entity/Q42810891

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

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SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

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type

label

SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

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SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

@nl

prefLabel

SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

@en

SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

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P356

P1433

Journal of Biological Chemistry

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SphK1 and SphK2, sphingosine k ...... ns in sphingolipid metabolism.

@en

P2093

Alfred H Merrill

http://www.w3.org/2001/XMLSchema#string

Claiborne Collier

http://www.w3.org/2001/XMLSchema#string

Heidi Sankala

http://www.w3.org/2001/XMLSchema#string

Hervé Le Stunff

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Hong Liu

http://www.w3.org/2001/XMLSchema#string

Leslie S Satin

http://www.w3.org/2001/XMLSchema#string

Michael Maceyka

http://www.w3.org/2001/XMLSchema#string

Min Zhang

http://www.w3.org/2001/XMLSchema#string

Nitai C Hait

http://www.w3.org/2001/XMLSchema#string

Rachelle Toman

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37118-37129

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scholarly article

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10.1074/JBC.M502207200

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44

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280

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2005-08-23T00:00:00Z

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16118219

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P921

Sphingosine kinase 1

Sphingosine kinase 2

Sphingosine kinase 2

negative regulation of ceramide biosynthetic process

Sphingosine kinase 1