Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals.
about
Transcriptional activation by Myc is under negative control by the transcription factor AP-2Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferationActivation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosisA core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum responseImmortalization of mouse neural precursor cells by the c-myc oncogeneOncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.Myc-mediated transformation: the repression connection.The first exon of the c-myc proto-oncogene contains a novel positive control element.Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.HMG-I/Y, a new c-Myc target gene and potential oncogeneConstitutive expression of c-myc oncogene confers hormone independence and enhanced growth-factor responsiveness on cells transformed by human papilloma virus type 16.A plasmacytoma-specific factor binds the c-myc promoter region.Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene.Polyomavirus-mediated transformation: a model of multistep carcinogenesis.Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-MycThe Cancer BioChip System: a functional genomic assay for anchorage-independent three-dimensional breast cancer cell growth.A transformation-associated 130-kD cell surface glycoprotein is growth controlled in normal human cellsRepression of cyclin D1: a novel function of MYCc-myc reverses neu-induced transformed morphology by transcriptional repression.The leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation.An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-mycA transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.Neoplastic transformation of mouse mammary epithelial cells by deregulated myc expression.L-myc cooperates with ras to transform primary rat embryo fibroblasts.Induction of clonal monocyte-macrophage tumors in vivo by a mouse c-myc retrovirus: rearrangement of the CSF-1 gene as a secondary transforming eventNeoplastic transformation by the human gene N-mycDefinition of regions in human c-myc that are involved in transformation and nuclear localization.Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation.A mouse c-myc retrovirus transforms established fibroblast lines in vitro and induces monocyte-macrophage tumors in vivo.Integration of the BALB/c ecotropic provirus into the colony-stimulating factor-1 growth factor locus in a myc retrovirus-induced murine monocyte tumorCooperative transforming activities of ras, myc, and src viral oncogenes in nonestablished rat adrenocortical cells.Generation and characterization of a recombinant Moloney murine leukemia virus containing the v-myc oncogene of avian MC29 virus: in vitro transformation and in vivo pathogenesisDifferential transformation of C3H10T1/2 cells by v-mos: sequential expression of transformation parameters.Synergism of v-myc and v-Ha-ras in the in vitro neoplastic progression of murine lymphoid cellsActivated v-myc and v-ras oncogenes do not transform normal human lymphocytes.Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53, or normal c-myc genesDifferential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factorRecombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens.Morphological transformation of established rodent cell lines by high-level expression of the adenovirus type 2 E1a gene.
P2860
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P2860
Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@en
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@nl
type
label
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@en
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@nl
prefLabel
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@en
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@nl
P2093
P1433
P1476
Fibroblast lines expressing ac ...... de mice and syngeneic animals.
@en
P2093
P304
P356
10.1016/0092-8674(84)90012-6
P407
P433
P577
1984-12-01T00:00:00Z