Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy. - Wikidata - awgldk - TriplyDB

Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy.

Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy.

http://www.wikidata.org/entity/Q42823179

about

The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4 The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease Small G proteins in the cardiovascular system: physiological and pathological aspects STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription Cardiac p300 is involved in myocyte growth with decompensated heart failure The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy Rho/ROCK signal cascade mediates asymmetric dimethylarginine-induced vascular smooth muscle cells migration and phenotype change.FOG-2 competes with GATA-4 for transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.Rho kinase as a therapeutic target in cardiovascular disease.NEXN inhibits GATA4 and leads to atrial septal defects in mice and humans.Electrical and mechanical stimulation of cardiac cells and tissue constructs.Role of the GATA family of transcription factors in endocrine development, function, and disease p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility.Increased Rho kinase activity in congestive heart failure.Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.RhoA-ROCK signaling is involved in contraction-mediated inhibition of SERCA2a expression in cardiomyocytes.Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy.ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK.Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.GATA4 regulates ANF expression synergistically with Sp1 in a cardiac hypertrophy model.Revisited and revised: is RhoA always a villain in cardiac pathophysiology?Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.MURC, a muscle-restricted coiled-coil protein, is involved in the regulation of skeletal myogenesis.Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.ERK activation by mechanical strain is regulated by the small G proteins rac-1 and rhoA.Identification and validation of an ERBB2 gene expression signature in breast cancers.Transcription factor GATA-4 is activated by phosphorylation of serine 261 via the cAMP/protein kinase a signaling pathway in gonadal cells.Substance P receptor antagonism: a potential novel treatment option for viral-myocarditis Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt.Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes.Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis.Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability.Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis.Mechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat.

P2860

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P2860

Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy.

http://www.wikidata.org/entity/Q42823179

description

2001 nî lūn-bûn

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2001年の論文

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2001年論文

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2001年論文

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2001年论文

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name

Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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type

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Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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prefLabel

Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

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P1433

Journal of Biological Chemistry

P1476

Rho/ROCK pathway contributes t ...... g myocardial cell hypertrophy.

@en

P2093

Hiromichi Wada

http://www.w3.org/2001/XMLSchema#string

Koji Hasegawa

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Mitsuru Abe

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Shigetake Sasayama

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Tatsuya Morimoto

http://www.w3.org/2001/XMLSchema#string

Teruhisa Kawamura

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Tetsuhiko Yanazume

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P2860

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

A p300 protein as a coactivator of GATA-6 in the transcription of the smooth muscle-myosin heavy chain gene

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload

P304

8618-8625

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scholarly article

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10.1074/JBC.M107924200

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10

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277

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2001-12-05T00:00:00Z

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11617931

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11739382

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