Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts.
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Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase CInsulin-induced phospholipase D1 and phospholipase D2 activity in human embryonic kidney-293 cells mediated by the phospholipase C gamma and protein kinase C alpha signalling cascadeTransmodulation between phospholipase D and c-Src enhances cell proliferationInteraction of phospholipase D1 with a casein-kinase-2-like serine kinaseRedox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cellsImplication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cellsActivation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and FgrGab1 is an integrator of cell death versus cell survival signals in oxidative stressPlant PIP2-dependent phospholipase D activity is regulated by phosphorylation.Requirement of phospholipase D1 activity in H-RasV12-induced transformationA comprehensive model that explains the regulation of phospholipase D2 activity by phosphorylation-dephosphorylation.The expression and cellular localization of phospholipase D isozymes in the developing mouse testisRole for mitochondrial oxidants as regulators of cellular metabolism.The uncovering of a novel regulatory mechanism for PLD2: formation of a ternary complex with protein tyrosine phosphatase PTP1B and growth factor receptor-bound protein GRB2.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells.Pulmonary fibrosis inducer, bleomycin, causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells.Redox signaling pathways involved in neuronal ischemic preconditioningPhosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1.Phospholipase D in platelets and other cells.Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase.Phospholipase D1 is up-regulated in the retina of Lewis rats with experimental autoimmune uveoretinitis.The TLR4-associated phospholipase D1 activation is crucial for Der f 2-induced IL-13 production.Insulin inhibits platelet-derived growth factor-induced cell proliferation.Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress.Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C.Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase DPhospholipase C-gamma1 is required for cell survival in oxidative stress by protein kinase C.MAP17, a ROS-dependent oncogene.Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation.Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling.Mitochondrial diacylglycerol initiates protein-kinase D1-mediated ROS signaling.Phospholipase D2 activity suppresses hydrogen peroxide-induced apoptosis in PC12 cells.Phospholipase D activation by norepinephrine is mediated by 12(s)-, 15(s)-, and 20-hydroxyeicosatetraenoic acids generated by stimulation of cytosolic phospholipase a2. tyrosine phosphorylation of phospholipase d2 in response to norepinephrine.Role of p38 MAP kinase in diperoxovanadate-induced phospholipase D activation in endothelial cells.Involvement of phospholipase D in oxidative stress-induced necrosis of vascular smooth muscle cells.Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq.Differential expression of phospholipase D isozymes in the hippocampus following kainic acid-induced seizures.
P2860
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P2860
Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@en
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@nl
type
label
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@en
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@nl
prefLabel
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@en
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@nl
P2093
P2860
P356
P1476
Involvement of tyrosine phosph ...... H2O2 in Swiss 3T3 fibroblasts.
@en
P2093
P2860
P304
29986-29994
P356
10.1074/JBC.273.45.29986
P407
P577
1998-11-01T00:00:00Z