Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.
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Molecular imaging of integrin αvβ6 expression in living subjects.Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membraneαvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.Synthesis and characterization of a high-affinity {alpha}v{beta}6-specific ligand for in vitro and in vivo applications.Correlations between integrin ανβ6 expression and clinico-pathological features in stage B and stage C rectal cancer.Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma.Role of alphavbeta6 integrin in acute biliary fibrosisThe coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.HMGB1 accelerates alveolar epithelial repair via an IL-1β- and αvβ6 integrin-dependent activation of TGF-β1Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation.Generation and characterization of a diabody targeting the αvβ6 integrin.Involvement of cholangiocyte proliferation in biliary fibrosis.Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.The αvβ6 integrin is transferred intercellularly via exosomesαVβ6 integrin promotes corneal wound healing.Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6α(V)β(6) integrin expression is induced in the POET and Pten(pc-/-) mouse models of prostatic inflammation and prostatic adenocarcinoma.Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosisAlphavbeta6 integrin in wound healing and cancer of the oral cavity.The alphaVbeta6 integrin as a novel molecular target for colorectal cancer.Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancerInduction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.Absence of alphavbeta6 integrin is linked to initiation and progression of periodontal diseaseReduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 ExpressionHigh expression of integrin β6 in association with the Rho-Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers.Mapping the epitopes of antibodies.Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders.Inhibition of human scleral fibroblast cell attachment to collagen type I by TGFBIpStromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.The role of integrins in cancer and the development of anti-integrin therapeutic agents for cancer therapy.Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis.Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis.Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.ImmunoPET Imaging of αvβ6 Expression Using an Engineered Anti-αvβ6 Cys-diabody Site-Specifically Radiolabeled with Cu-64: Considerations for Optimal Imaging with Antibody Fragments.Specificity of the VP1 GH loop of Foot-and-Mouth Disease virus for alphav integrins.
P2860
Q27007536-C417677A-80F0-4CF9-B42C-06437FB6CCB1Q27316196-28EFA0DC-8070-4460-943D-E368EF6807D9Q30276295-C6FE6561-EC1E-4D81-9B45-04C6AD70ED3FQ33444443-134CAD1D-AFB0-448C-A02D-C81B6B90C69DQ33599336-43B7DD38-768D-4F98-B0E7-9D84086598A2Q33631115-124E1F6B-83BC-4CDF-8E97-74D8EDA7C25CQ33731789-460587B7-7897-44C4-91C7-221D243172A9Q34088326-BAFBCD38-0535-4D49-B5FD-97F54EDFF252Q34358154-5966BDB7-E8E9-4A3C-9005-B434F1EF86B7Q34619626-83D73B88-6F93-4272-A51F-DEA353B76CF9Q34734005-BB373E72-33BF-4D59-9276-F76431EB056FQ34737849-5841D60C-5E7C-4E76-BD01-20DA798C69F6Q34984328-9A16AF8A-9C88-4C6B-A822-C161FB8C2EE6Q34992326-798CE650-11B8-4808-B73D-9EE5C52538F2Q35002110-6EC19D87-EEEF-4EEA-85E6-92A2811CD8CDQ35103855-FB7DD143-A086-46BF-868B-8BCE4842B032Q35524640-FA658326-C11B-407F-9D1E-CF89D33A2464Q35570438-9BBD7FB4-58DE-460F-9D83-93DA72538314Q35857048-9FB72CDB-8F07-4AA0-8343-EAE262FB8A1BQ35964178-7CCFEB92-4AB8-4D31-89F5-48EC4AE61F05Q36330655-9A6B44D7-DC95-4DB3-A015-695C3B324AF5Q36360521-B06093D7-B6A2-4E86-94FB-7CAD0E98B8A8Q36429644-33CD331C-E1BC-4067-A264-CC6AD64C5463Q36484576-953F4275-C81B-46C6-9501-8B2B2DCAF2D7Q36512337-8261898D-BBD8-460E-94E2-1415C34F3A23Q36579815-CEE80A03-8985-4C48-9A11-58F754A35E6BQ36850011-37D68008-BE1A-4353-A029-F0C39F349F5FQ36918650-1E399A3E-7585-4328-A2C5-036F0922EAACQ37024671-D54348AA-F2FA-4AF4-94CB-1161A45AE1E5Q37343785-34ECA088-2B59-4E19-B555-3B97E367FF7FQ37362030-0C275CE7-9158-45AD-8E64-1C5841F57F23Q37365094-D6C42591-2D97-448B-BFF8-93A236BDCEDBQ37468713-2614F7C0-AE21-4E6D-A3BD-B7B9269B3BB6Q37603527-B4BF9E37-424A-429E-8F4C-25F4916D4267Q37604903-C4D29A61-2E17-4D99-9841-515772E3EB7BQ37644463-A83E5006-8717-4CB6-BD46-232C8C0FADDAQ37707603-43F24A12-4073-4DC6-BE8E-8DC66BE4E67FQ38537769-63D1335C-B765-4EE6-AF0D-83F8DDA3232EQ38666311-A4EDBF68-04B0-4EB5-BA1E-A07560663665Q38760885-4048BFA4-9302-4203-BB36-42C8493B44D4
P2860
Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@en
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@nl
type
label
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@en
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@nl
prefLabel
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@en
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@nl
P2093
P2860
P356
P1476
Function-blocking integrin alp ...... and nonligand-mimetic classes.
@en
P2093
Amha Atakilit
Bradley R Pearse
Brian M Dolinski
Dean Sheppard
Diane R Leone
Hisaaki Kawakatsu
Kenneth J Simon
Paul Rayhorn
Shelia M Violette
William J Yang
P2860
P304
17875-17887
P356
10.1074/JBC.M312103200
P407
P577
2004-02-11T00:00:00Z