Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.
about
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cellsI-SceI-induced gene replacement at a natural locus in embryonic stem cellsProcessing of DNA for nonhomologous end-joining by cell-free extractGeneration of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffoldsChromosomal double-strand break repair in Ku80-deficient cellsTargeted transgenesisDNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cellsRepair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombinationEfficient targeting of a SCID gene by an engineered single-chain homing endonucleaseA combinatorial approach to create artificial homing endonucleases cleaving chosen sequencesIn vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationRNA Interference in the Age of CRISPR: Will CRISPR Interfere with RNAi?Towards a new era in medicine: therapeutic genome editingApplications of CRISPR-Cas systems in neuroscienceOrigins of Programmable Nucleases for Genome EngineeringEnabling functional genomics with genome engineeringEngineering large animal models of human diseaseDesigned nucleases for targeted genome editingRepair of strand breaks by homologous recombinationRewriting the blueprint of life by synthetic genomics and genome engineeringInflammation-induced cell proliferation potentiates DNA damage-induced mutations in vivoThe C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavageExpanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence spaceImplication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.The application of genome editing in studying hearing lossMicrohomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsTherapeutic genome editing: prospects and challengesMammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombinationRepair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cellsDevelopment and applications of CRISPR-Cas9 for genome engineering.Gene targeting using zinc finger nucleasesMitotic homologous recombination maintains genomic stability and suppresses tumorigenesisGenome editing with engineered zinc finger nucleasesMutants of Cre recombinase with improved accuracyOligo/polynucleotide-based gene modification: strategies and therapeutic potentialStructure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleasesMycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repairI-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cellsMsh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae
P2860
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P2860
Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Introduction of double-strand ...... f a rare-cutting endonuclease.
@en
Introduction of double-strand ...... f a rare-cutting endonuclease.
@nl
type
label
Introduction of double-strand ...... f a rare-cutting endonuclease.
@en
Introduction of double-strand ...... f a rare-cutting endonuclease.
@nl
prefLabel
Introduction of double-strand ...... f a rare-cutting endonuclease.
@en
Introduction of double-strand ...... f a rare-cutting endonuclease.
@nl
P2093
P2860
P356
P1476
Introduction of double-strand ...... f a rare-cutting endonuclease.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.12.8096
P407
P577
1994-12-01T00:00:00Z