KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
about
Latently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase.A Kaposi's sarcoma-associated herpesviral protein inhibits virus-mediated induction of type I interferon by blocking IRF-7 phosphorylation and nuclear accumulation.Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon/retinoic acid-induced cell death.Antiviral actions of interferonsIdentification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirusInterferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytesThe IRF family, revisitedThe Role of Gammaherpesviruses in Cancer PathogenesisDoes EBV alter the pathogenesis of malaria?Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomersThe crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factorMulti-step regulation of innate immune signaling by Kaposi's sarcoma-associated herpesvirusMolecular virology of Kaposi's sarcoma-associated herpesvirusIntracellular Kaposi's sarcoma-associated herpesvirus load determines early loss of immune synapse components.Kaposi's Sarcoma–Associated Herpesvirus Immunoevasion and Tumorigenesis: Two Sides of the Same Coin?Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma-associated herpesvirus.Complex alternative cytoplasmic protein isoforms of the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 generated through noncanonical translation initiation.Molecular biology of KSHV in relation to AIDS-associated oncogenesis.Increased tumorigenicity of cells carrying recombinant human herpesvirus 8.Early and sustained expression of latent and host modulating genes in coordinated transcriptional program of KSHV productive primary infection of human primary endothelial cells.Alpha interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cellsFunctional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300.Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice.Perspective on Kaposi's sarcoma: facts, concepts, and conjectures.KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine.Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) transforming geneKaposi's sarcoma-associated herpesvirus LANA2 is a B-cell-specific latent viral protein that inhibits p53Transcription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis.Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesisSpectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseasesInhibition of p300 histone acetyltransferase by viral interferon regulatory factor.Interferon regulatory factor 4 contributes to transformation of v-Rel-expressing fibroblastsBim nuclear translocation and inactivation by viral interferon regulatory factor.Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1)Evolutionary aspects of oncogenic herpesvirusesKaposi's sarcoma: aetiopathogenesis, histology and clinical features.Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.Rigid interferon-alpha subtype responses of human plasmacytoid dendritic cells.Kaposi's sarcoma-associated herpesvirus ORF18 and ORF30 are essential for late gene expression during lytic replication.
P2860
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P2860
KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
@en
KSHV ORF K9
@nl
type
label
KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
@en
KSHV ORF K9
@nl
prefLabel
KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
@en
KSHV ORF K9
@nl
P2093
P356
P1433
P1476
KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1201571
P407
P577
1997-10-01T00:00:00Z
P5875
P6179
1000554961