Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation.
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Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascadesRaf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanismA novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartmentERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformationIdentification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK bindingAdenosine kinase regulation of cardiomyocyte hypertrophy.RSK2 protein suppresses integrin activation and fibronectin matrix assembly and promotes cell migrationIntegrins promote cytokinesis through the RSK signaling axis.Raf-1 signaling is required for the later stages of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK moduleSuppression of integrin activation by activated Ras or Raf does not correlate with bulk activation of ERK MAP kinase.Somatic p16(INK4a) loss accelerates melanomagenesisCyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signalsRas/Raf signalling and emerging pharmacotherapeutic targets.Role of mitogen- and stress-activated kinases in ischemic injury.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component.Raf kinases: function, regulation and role in human cancer.The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivoTNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB.Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaBHow ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis.KRAS and BRAF: drug targets and predictive biomarkers.Analysis of the ERK1,2 transcriptome in mammary epithelial cellsInducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation.Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation.Transforming growth factor beta1 is up-regulated by activated Raf in skeletal myoblasts but does not contribute to the differentiation-defective phenotype.Time Course Expression Analysis of 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole Induction of Cytoprotection in Human Endothelial Cells.Activation of FGF2-FGFR signaling in the castrated mouse prostate stimulates the proliferation of basal epithelial cells.A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation.Raf-1 without MEK?Inhibition of myogenin expression by activated Raf is not responsible for the block to avian myogenesis.PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.
P2860
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P2860
Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@en
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@nl
type
label
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@en
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@nl
prefLabel
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@en
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@nl
P2093
P2860
P356
P1476
Uncoupling Raf1 from MEK1/2 im ...... r responses to Raf activation.
@en
P2093
P2860
P304
37303-37306
P356
10.1074/JBC.C000570200
P407
P577
2000-12-01T00:00:00Z