A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.

Item
http://www.wikidata.org/entity/Q42836096
Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-IAltered affinity of insulin-like growth factor II (IGF-II) for receptors and IGF-binding proteins, resulting from limited modifications of the IGF-II moleculeThe insulin-like growth factor (IGF)binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysisOpposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts.Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?Insulin-like growth factors I and II.Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate.BIAcore analysis of bovine insulin-like growth factor (IGF)-binding protein-2 identifies major IGF binding site determinants in both the amino- and carboxyl-terminal domains.A mutant of human insulin-like growth factor II (IGF II) with the processing sites of proinsulin. Expression and binding studies of processed IGF II.The biological role of truncated insulin-like growth factor-1 and the tripeptide GPE in the central nervous system.Binding affinities of insulin-like growth factor-I (IGF-I) fusion proteins to IGF binding protein 1 and IGF-I receptor are not correlated with mitogenic activity.Insulin-like growth factor-II is a substrate for dipeptidylpeptidase I (cathepsin C). Biological properties of the product.Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions.Mutations in the B-domain of insulin-like growth factor-I influence the oxidative folding to yield products with modified biological propertiesAlanine screening mutagenesis establishes tyrosine 60 of bovine insulin-like growth factor binding protein-2 as a determinant of insulin-like growth factor binding.The Insulin-like Growth Factor (IGF) Binding Site of Bovine Insulin-like Growth Factor Binding Protein-2 (bIGFBP-2) Probed by Iodination
P2860

A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.

Item
http://www.wikidata.org/entity/Q42836096
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@en
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@nl
type
label
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@en
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@nl
prefLabel
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@en
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
A key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932