Metalloproteinase digestion of cartilage proteoglycan. Pattern of cleavage by stromelysin and susceptibility to collagenase.
about
Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domainMatrix metalloproteinases cleave at two distinct sites on human cartilage link proteinAge-related changes in the content of the C-terminal region of aggrecan in human articular cartilageActivation of precursors for matrix metalloproteinases 1 (interstitial collagenase) and 3 (stromelysin) by rat mast-cell proteinases I and IIStromelysin 1, neutrophil collagenase, and collagenase 3 do not play major roles in a model of chondrocyte mediated cartilage breakdown.Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity.Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391.Proteoglycan loss and subsequent replenishment in articular cartilage after a mild arthritic insult by IL-1 in mice: impaired proteoglycan turnover in the recovery phase.Human cartilage aggrecan CS1 region contains cryptic T-cell recognition sites.An N-terminal peptide from link protein is rapidly degraded by chondrocytes, monocytes and B cells.Characterization of proteoglycans isolated from associative extracts of human articular cartilage.Culture duration modulates collagen hydrolysate-induced tissue remodeling in chondrocyte-seeded agarose hydrogels.Cellular invasion and collagen type IX in the primary corneal stroma in vitro.
P2860
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P2860
Metalloproteinase digestion of cartilage proteoglycan. Pattern of cleavage by stromelysin and susceptibility to collagenase.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Metalloproteinase digestion of ...... susceptibility to collagenase.
@en
Metalloproteinase digestion of ...... susceptibility to collagenase.
@nl
type
label
Metalloproteinase digestion of ...... susceptibility to collagenase.
@en
Metalloproteinase digestion of ...... susceptibility to collagenase.
@nl
prefLabel
Metalloproteinase digestion of ...... susceptibility to collagenase.
@en
Metalloproteinase digestion of ...... susceptibility to collagenase.
@nl
P2860
P356
P1433
P1476
Metalloproteinase digestion of ...... susceptibility to collagenase.
@en
P2093
P2860
P304
P356
10.1042/BJ2790733
P407
P478
279 ( Pt 3)
P577
1991-11-01T00:00:00Z