Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling. - Wikidata - awgldk - TriplyDB

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

http://www.wikidata.org/entity/Q42863016

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SIRT3 regulates progression and development of diseases of aging.SIRT3 in Cardiac Physiology and Disease Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function.Lysine Acetylation Activates Mitochondrial Aconitase in the Heart Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial Infarction High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss.Successful metabolic adaptations leading to the prevention of high fat diet-induced murine cardiac remodeling Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich's ataxia cardiomyopathy.Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart.Novel targets for mitochondrial medicine.Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro.Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.Acetylation and succinylation contribute to maturational alterations in energy metabolism in the newborn heart.Mitochondrial sirtuins in the heart.Mechanisms of transcription factor acetylation and consequences in hearts.Aspirin increases mitochondrial fatty acid oxidation.Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice.Receptor-interacting Protein 140 represses Sirtuin 3 to facilitate hypertrophy, mitochondrial dysfunction and energy metabolic dysfunction in cardiomyocytes.Methylene blue decreases mitochondrial lysine acetylation in the diabetic heart Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes.Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats Metabolic Origins of Heart Failure.Manifestations and mechanisms of myocardial lipotoxicity in obesity.Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake.Revisiting protein acetylation and myocardial fatty acid oxidation.SIRT3 deficiency impairs mitochondrial and contractile function in the heart.GCN5L1/BLOS1 Links Acetylation, Organelle Remodeling, and Metabolism.SIRT3: A New Regulator of Cardiovascular Diseases.The Regulation of Insulin-Stimulated Cardiac Glucose Transport via Protein Acetylation.Loss of Metabolic Flexibility in the Failing Heart.Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism.The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA Investigation of post-translational modifications in type 2 diabetes PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3

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Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

http://www.wikidata.org/entity/Q42863016

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

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Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

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type

label

Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

@en

Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

@nl

prefLabel

Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

@en

Obesity-induced lysine acetyla ...... nd impairs insulin signalling.

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Cardiovascular Research

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Obesity-induced lysine acetyla ...... and impairs insulin signalling

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P2093

Arya M Sharma

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Cary Ma

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Cory S Wagg

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David E Johnstone

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Evangelos D Michelakis

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Gary D Lopaschuk

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Jagdip S Jaswal

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Mahesh P Gupta

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Michael N Sack

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Natasha Fillmore

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P2860

Regulation of cellular metabolism by protein lysine acetylation

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1

SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation

Obesity and insulin resistance

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase

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485-497

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10.1093/CVR/CVU156

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4

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103

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24966184

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4155471

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