about
Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedbackLung ultrasonography as a direct measure of evolving respiratory dysfunction and disease severity in patients with acute pancreatitis.Electronic patient data confidentiality practices among surgical trainees: questionnaire studyMesenteric lymph duct ligation decreases red blood cell alterations caused by acute pancreatitis.Early organ dysfunction affects long-term survival in acute pancreatitis patients.Detailed fluid resuscitation profiles in patients with severe acute pancreatitisKynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases.A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery.Identifying risk factors for progression to critical care admission and death among individuals with acute pancreatitis: a record linkage analysis of Scottish healthcare databases.Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records.Increased levels of 3-hydroxykynurenine parallel disease severity in human acute pancreatitis.Bacterial expression of human kynurenine 3-monooxygenase: solubility, activity, purification.Lead discovery for human kynurenine 3-monooxygenase by high-throughput RapidFire mass spectrometry.ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenaseThe intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitisElectronic data protection: procedures need drastic improvement.Alcohol and global health: focus on acute pancreatitis needed.Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.Differential preservation of lipopolysaccharide-induced chemokine/cytokine expression during experimental pancreatitis-associated organ failure in rats shows a regulatory expressed phenotype.The isolated perfused liver response to a 'second hit' of portal endotoxin during severe acute pancreatitis.Tryptophan catabolites in mesenteric lymph may contribute to pancreatitis-associated organ failure.Detecting drug-target binding in cells using fluorescence-activated cell sorting coupled with mass spectrometry analysis.Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo.Anatomical orientation and cross-checking-the key to safer laparoscopic cholecystectomy.111Indium-labelled red-cell scintigraphy to detect intermittent gastrointestinal bleeding from synchronous small- and large-bowel adenocarcinomas.Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibition During Sepsis Dampens the Early Systemic Inflammatory Response.Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.Descending aortic dissection post coarctation repair in a patient with Turner's syndrome.Delayed paraplegia after endovascular repair of abdominal aortic aneurysm.Once bitten, twice shy: defective monocyte signaling in acute pancreatitis.Emergency general surgery 'Hot Clinics' reduce admission rates and duration of inpatient stay.Study protocol: HepaT1ca - an observational clinical cohort study to quantify liver health in surgical candidates for liver malignanciesThe discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitisSurvival and new-onset morbidity after critical care admission for acute pancreatitis in Scotland: a national electronic healthcare record linkage cohort studyKynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injuryMultiomic definition of generalizable endotypes in human acute pancreatitis
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Damian Mole
@ast
Damian Mole
@en
Damian Mole
@es
Damian Mole
@nl
Damian Mole
@sl
type
label
Damian Mole
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Damian Mole
@en
Damian Mole
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Damian Mole
@nl
Damian Mole
@sl
prefLabel
Damian Mole
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Damian Mole
@en
Damian Mole
@es
Damian Mole
@nl
Damian Mole
@sl
P106
P1153
7006082611
P21
P31
P496
0000-0001-6884-7302