about
Imputation and subset based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.335-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs.An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancerCLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cellsLomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching.Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A.Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy.A resequence analysis of genomic loci on chromosomes 1q32.1, 5p15.33, and 13q22.1 associated with pancreatic cancer risk.Properties of Nat4, an N(alpha)-acetyltransferase of Saccharomyces cerevisiae that modifies N termini of histones H2A and H4RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p.Mechanistic approach for the prediction of structural response due to subsidenceEvidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jason Hoskins
@ast
Jason Hoskins
@en
Jason Hoskins
@es
Jason Hoskins
@nl
Jason Hoskins
@sl
type
label
Jason Hoskins
@ast
Jason Hoskins
@en
Jason Hoskins
@es
Jason Hoskins
@nl
Jason Hoskins
@sl
prefLabel
Jason Hoskins
@ast
Jason Hoskins
@en
Jason Hoskins
@es
Jason Hoskins
@nl
Jason Hoskins
@sl
P1053
F-5672-2012
P106
P1153
7103063440
P21
P31
P3829
P3835
jason-hoskins
P496
0000-0001-6944-1996