about
DNA damage responses following exposure to modulated radiation fieldsRoadmap to Clinical Use of Gold Nanoparticles for Radiation Sensitization.Investigation into the radiobiological consequences of pre-treatment verification imaging with megavoltage X-rays in radiotherapyA robust curve-fitting procedure for the analysis of plasmid DNA strand break data from gel electrophoresis.A kinetic-based model of radiation-induced intercellular signalling.The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.Imaging and radiation effects of gold nanoparticles in tumour cellsComparing stochastic proton interactions simulated using TOPAS-nBio to experimental data from fluorescent nuclear track detectors.Physical basis and biological mechanisms of gold nanoparticle radiosensitization.Relative biological effectiveness variation along monoenergetic and modulated Bragg peaks of a 62-MeV therapeutic proton beam: a preclinical assessment.A novel CBCT-based method for derivation of CTV-PTV margins for prostate and pelvic lymph nodes treated with stereotactic ablative radiotherapy.An overview of current practice in external beam radiation oncology with consideration to potential benefits and challenges for nanotechnology.Protein disulphide isomerase as a target for nanoparticle-mediated sensitisation of cancer cells to radiation.Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage.Time and Cell Type Dependency of Survival Responses in Co-cultured Tumor and Fibroblast Cells after Exposure to Modulated Radiation Fields.Conventional in vivo irradiation procedures are insufficient to accurately determine tumor responses to non-uniform radiation fields.Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions.Investigating the influence of respiratory motion on the radiation induced bystander effect in modulated radiotherapy.Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticlesAn in vitro study of the radiobiological effects of flattening filter free radiotherapy treatments.Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries.In-vitro investigation of out-of-field cell survival following the delivery of conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans.Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles.Implications of intercellular signaling for radiation therapy: a theoretical dose-planning study.Dose, dose-rate and field size effects on cell survival following exposure to non-uniform radiation fields.A computational model of cellular response to modulated radiation fields.Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy.Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest.Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol.A general mechanistic model enables predictions of the biological effectiveness of different qualities of radiation.Prostate cancer treated with brachytherapy; an exploratory study of dose-dependent biomarkers and quality of life.Gold nanoparticle induced vasculature damage in radiotherapy: Comparing protons, megavoltage photons, and kilovoltage photons.A mechanistic study of gold nanoparticle radiosensitisation using targeted microbeam irradiation.The role of mitochondrial function in gold nanoparticle mediated radiosensitisation.Modelling responses to spatially fractionated radiation fields using preclinical image-guided radiotherapy.Small field dosimetry for the small animal radiotherapy research platform (SARRP).Dual effects of radiation bystander signaling in urothelial cancer: purinergic-activation of apoptosis attenuates survival of urothelial cancer and normal urothelial cells.Comment on 'implications on clinical scenario of gold nanoparticle radiosensitization in regard to photon energy, nanoparticle size, concentration and location'.The Impact of Hypoxia on Out-of-Field Cell Survival after Exposure to Modulated Radiation Fields.The Radiobiology of Proton Therapy: Challenges and Opportunities Around Relative Biological Effectiveness.
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description
hulumtues
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researcher
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հետազոտող
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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McMahon SJ
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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Stephen J. McMahon
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P106
P1153
35737693200
P21
P31
P496
0000-0001-5980-6728