about
Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropesA novel human ghrelin variant (In1-ghrelin) and ghrelin-O-acyltransferase are overexpressed in breast cancer: potential pathophysiological relevance.Somatostatin and its receptors from fish to mammals.Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed miceDifferential impact of selective GH deficiency and endogenous GH excess on insulin-mediated actions in muscle and liver of male mice.Role of endogenous cortistatin in the regulation of ghrelin system expression at pancreatic level under normal and obese conditions.Melatonin regulates somatotrope and lactotrope function through common and distinct signaling pathways in cultured primary pituitary cells from female primatesObesity alters gene expression for GH/IGF-I axis in mouse mammary fat pads: differential role of cortistatin and somatostatin.Kisspeptin regulates gonadotroph and somatotroph function in nonhuman primate pituitary via common and distinct signaling mechanismsRole of ghrelin system in neuroprotection and cognitive functions: implications in Alzheimer's disease.Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.Cortistatin is not a somatostatin analogue but stimulates prolactin release and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin.Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult MiceDoes the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes?The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female miceHepatic PPARγ Is Not Essential for the Rapid Development of Steatosis After Loss of Hepatic GH Signaling, in Adult Male MiceEndogenous somatostatin is critical in regulating the acute effects of L-arginine on growth hormone and insulin release in mice.Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity?Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia and adenoma formation due to GHRH-receptor hyperactivation.Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice.Understanding the multifactorial control of growth hormone release by somatotropes: lessons from comparative endocrinology.Long- but not short-term adult-onset, isolated GH deficiency in male mice leads to deterioration of β-cell function, which cannot be accounted for by changes in β-cell mass.Obestatin plays an opposite role in the regulation of pituitary somatotrope and corticotrope function in female primates and male/female mice.Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass.Somatostatin dramatically stimulates growth hormone release from primate somatotrophs acting at low doses via somatostatin receptor 5 and cyclic AMP.Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammation.Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients.Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach.Cortistatin Is a Key Factor Regulating the Sex-Dependent Response of the GH and Stress Axes to Fasting in Mice.Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice.Not So Giants: Mice Lacking Both Somatostatin and Cortistatin Have High GH Levels but Show No Changes in Growth Rate or IGF-1 Levels.Growth Hormone Control of Hepatic Lipid Metabolism.Fasting modulates GH/IGF-I axis and its regulatory systems in the mammary gland of female mice: Influence of endogenous cortistatin.Adult-onset hepatocyte GH resistance promotes NASH in male mice, without severe systemic metabolic dysfunctionImpact of gsp Oncogene on the mRNA Content for Somatostatin and Dopamine Receptors in Human SomatotropinomasHepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant miceAutophagy Differentially Regulates Insulin Production and Insulin SensitivityHepatic HKDC1 Expression Contributes to Liver Metabolism
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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type
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José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
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prefLabel
José Córdoba-Chacón
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José Córdoba-Chacón
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José Córdoba-Chacón
@es
José Córdoba-Chacón
@nl
José Córdoba-Chacón
@sl
P106
P21
P31
P496
0000-0001-8787-2706