Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast.
about
A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolismRibosome-based quality control of mRNA and nascent peptidesRibosome-associated protein quality controlThe Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality ControlA ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stressCdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products.Protein quality control systems associated with no-go and nonstop mRNA surveillance in yeast.Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains.The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation.Role of a ribosome-associated E3 ubiquitin ligase in protein quality controlCdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome.Reprogramming the genetic code: The emerging role of ribosomal frameshifting in regulating cellular gene expressionListerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociationSignal peptide-dependent inhibition of MHC class I heavy chain translation by rhesus cytomegalovirusInitiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome UbiquitinationZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal UbiquitylationStructural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation.Reconstitution of a minimal ribosome-associated ubiquitination pathway with purified factorsPositively charged residues are the major determinants of ribosomal velocityBirth, life and death of nascent polypeptide chains.Genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation.Ribosomes slide on lysine-encoding homopolymeric A stretchesGlobal analysis of RNA cleavage by 5'-hydroxyl RNA sequencing.Ubiquitination of newly synthesized proteins at the ribosome.The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum Proteins.New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA.Degradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary DisordersLectin binding of human sperm associates with DEFB126 mutation and serves as a potential biomarker for subfertilityIntegrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing.Degradation of mRNAs that lack a stop codon: a decade of nonstop progressThe Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells.Quality control of bacterial mRNA decoding and decay.Diverse aberrancies target yeast mRNAs to cytoplasmic mRNA surveillance pathwaysRqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits.Electrostatics in the ribosomal tunnel modulate chain elongation rates.Viral Evasion and Manipulation of Host RNA Quality Control Pathways.Distinct types of translation termination generate substrates for ribosome-associated quality control.
P2860
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P2860
Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Translation of the poly
@nl
Translation of the poly(A) tai ...... zation by proteasome in yeast.
@en
type
label
Translation of the poly
@nl
Translation of the poly(A) tai ...... zation by proteasome in yeast.
@en
prefLabel
Translation of the poly
@nl
Translation of the poly(A) tai ...... zation by proteasome in yeast.
@en
P2093
P2860
P356
P1433
P1476
Translation of the poly(A) tai ...... zation by proteasome in yeast.
@en
P2093
Kazushige Kuroha
Sayoko Ito-Harashima
Toshifumi Inada
Tsuyako Tatematsu
P2860
P304
P356
10.1101/GAD.1490207
P577
2007-03-01T00:00:00Z