The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid.
about
The anti-inflammatory drug indomethacin alters nanoclustering in synthetic and cell plasma membranes.Meconium impairs pulmonary surfactant by a combined action of cholesterol and bile acids.Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Bile acids modulate signaling by functional perturbation of plasma membrane domains.Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.Anticancer steroids: linking natural and semi-synthetic compounds.Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs.Optimization of the Ussing chamber setup with excised rat intestinal segments for dissolution/permeation experiments of poorly soluble drugs.Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.Advent of novel phosphatidylcholine-associated nonsteroidal anti-inflammatory drugs with improved gastrointestinal safety.Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms.Higher fecal bile acid hydrophobicity is associated with exacerbation of dextran sodium sulfate colitis in mice
P2860
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P2860
The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@en
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@nl
type
label
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@en
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@nl
prefLabel
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@en
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@nl
P2093
P2860
P1476
The role of membrane cholester ...... ction of ursodeoxycholic acid.
@en
P2093
Lenard M Lichtenberger
Rand Doyen
P2860
P304
P356
10.1016/J.BBAMEM.2008.12.008
P577
2008-12-25T00:00:00Z