Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival.
about
ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in miceRole of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acidsDual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formationA role for ELOVL4 in the mouse meibomian gland and sebocyte cell biology.Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprintDistribution of ELOVL4 in the Developing and Adult Mouse Brain.Inner retina remodeling in a mouse model of stargardt-like macular dystrophy (STGD3).Retinal very long-chain PUFAs: new insights from studies on ELOVL4 proteinElovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrityDefective lipid transport and biosynthesis in recessive and dominant Stargardt macular degenerationRole of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophiesElovl6: a new player in fatty acid metabolism and insulin sensitivity.Genetics and molecular pathology of Stargardt-like macular degeneration.Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.Role of Elovl4 protein in the biosynthesis of docosahexaenoic acidDepletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient miceAntibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria.Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function.EGFR regulation of epidermal barrier function.Nrf2 links epidermal barrier function with antioxidant defenseThe acyl-CoA binding protein is required for normal epidermal barrier function in mice.A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholinesDeciphering mutant ELOVL4 activity in autosomal-dominant Stargardt macular dystrophy.Clinical characterization and genetic mapping of North Carolina macular dystrophy.Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid productionThe outer frontier: the importance of lipid metabolism in the skinFatty acid metabolism: Implications for diet, genetic variation, and disease.Very long chain sphingolipids: tissue expression, function and synthesis.Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.Association between P478S polymorphism of the filaggrin gene & atopic dermatitis.Fatty aldehyde and fatty alcohol metabolism: review and importance for epidermal structure and function.In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4.Functional Characterization of Two Elongases of Very Long-Chain Fatty Acid from Tenebrio molitor L. (Coleoptera: Tenebrionidae).Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury.Elongation of very Long-Chain (>C24) Fatty Acids in Clarias gariepinus: Cloning, Functional Characterization and Tissue Expression of elovl4 ElongasesSite-directed mutagenesis of a fatty acid elongase ELO-like condensing enzyme.Elovl4 5-bp deletion does not accelerate cone photoreceptor degeneration in an all-cone mouse.Sphingolipids and their metabolism in physiology and disease.Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency.
P2860
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P2860
Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@en
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@nl
type
label
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@en
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@nl
prefLabel
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@en
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@nl
P2093
P2860
P356
P1476
Essential role of Elovl4 in ve ...... nction, and neonatal survival.
@en
P2093
D Joshua Cameron
Haoyu Chen
Jack Kaminoh
Jiexi Zeng
Kang Zhang
Shin Kamiyah
Zhenglin Yang
Zongzhong Tong
P2860
P304
P356
10.7150/IJBS.3.111
P407
P577
2007-02-06T00:00:00Z