Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly.
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Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and functionIFT-Cargo Interactions and Protein Transport in CiliaMutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilizationIFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndromeIFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration.IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.Chlamydomonas axonemal dynein assembly locus ODA8 encodes a conserved flagellar protein needed for cytoplasmic maturation of outer dynein arm complexesThe more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathiesIFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype.Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging.The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signalingOverall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral SubcomplexDestabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.The X-linked deubiquitinase USP9X is an integral component of centrosome.The Intraflagellar Transport Machinery.Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46.Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.The trafficking of bacterial type rhodopsins into the Chlamydomonas eyespot and flagella is IFT mediated.The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.Recombinant Reconstitution and Purification of the IFT-B Core Complex from Chlamydomonas reinhardtii.Rab GTPases in cilium formation and function.The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16.IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.A homozygous nonsense variant in IFT52 is associated with a human skeletal ciliopathy.Assembly of IFT B complexCrystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility
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Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly.
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
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@zh-cn
name
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@en
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@nl
type
label
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@en
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@nl
prefLabel
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@en
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@nl
P2860
P50
P356
P1476
Crystal structures of IFT70/52 ...... sport B core complex assembly.
@en
P2093
E Wolfgang Kuehn
Fruzsina Kotsis
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P304
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10.1083/JCB.201408002
P407
P577
2014-10-01T00:00:00Z