Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice.
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RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cellsRole of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson's Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties.The protective effect of lactoferrin on ventral mesencephalon neurons against MPP + is not connected with its iron binding ability.Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands.Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice.Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Toll-like receptors 2, -3 and -4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1β release.Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson's disease.Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair.The role of neuroinflammation in dementias.The prion hypothesis of Parkinson's disease.Blue Light Modulates Murine Microglial Gene Expression in the Absence of Optogenetic Protein Expression.Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?Potential repositioning of exemestane as a neuroprotective agent for Parkinson's disease.GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF- κ B Pathways in LPS-Stimulated Microglial CellsActivation of Sonic hedgehog signal by Purmorphamine, in a mouse model of Parkinson's disease, protects dopaminergic neurons and attenuates inflammatory response by mediating PI3K/AKt signaling pathwayMicroglial phenotypes in Parkinson's disease and animal models of the disease.6-Mer Hyaluronan Oligosaccharides Modulate Neuroinflammation and α-Synuclein Expression in Neuron-Like SH-SY5Y Cells.Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia.Parkinson's disease: Microglial/macrophage-induced immunoexcitotoxicity as a central mechanism of neurodegenerationThe potential role of neuroinflammation and transcription factors in Parkinson diseaseDopaminergic Regulation of Innate Immunity: a Review.Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement.Persistent inflammatory state after photoreceptor loss in an animal model of retinal degeneration.PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2.Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson's disease.Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson's disease model.An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.Minocycline Rescues from Zinc-Induced Nigrostriatal Dopaminergic Neurodegeneration: Biochemical and Molecular Interventions.A nucleoprotein-enriched diet suppresses dopaminergic neuronal cell loss and motor deficit in mice with MPTP-induced Parkinson's disease.Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways.SIRT2 Plays Significant Roles in Lipopolysaccharides-Induced Neuroinflammation and Brain Injury in Mice.Inhibition of Rho-kinase by Fasudil protects dopamine neurons and attenuates inflammatory response in an intranasal lipopolysaccharide-mediated Parkinson's model.Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson's disease.Anti-Neuroinflammatory Effect of MC13, a Novel Coumarin Compound From Condiment Murraya, Through Inhibiting Lipopolysaccharide-Induced TRAF6-TAK1-NF-κB, P38/ERK MAPKS and Jak2-Stat1/Stat3 Pathways.Serum amyloid A primes microglia for ATP-dependent interleukin-1β release.HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway.An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways
P2860
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P2860
Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Activation of microglia induce ...... but not in IL-1 knockout mice.
@en
Activation of microglia induce ...... but not in IL-1 knockout mice.
@nl
type
label
Activation of microglia induce ...... but not in IL-1 knockout mice.
@en
Activation of microglia induce ...... but not in IL-1 knockout mice.
@nl
prefLabel
Activation of microglia induce ...... but not in IL-1 knockout mice.
@en
Activation of microglia induce ...... but not in IL-1 knockout mice.
@nl
P2093
P2860
P921
P356
P1476
Activation of microglia induce ...... but not in IL-1 knockout mice.
@en
P2093
Atsuko Ishii
Hirokazu Ohtaki
Sachiko Tanaka
Satoshi Numazawa
Seiji Shioda
Takemi Yoshida
P2860
P2888
P356
10.1186/1742-2094-10-143
P577
2013-12-01T00:00:00Z
P5875
P6179
1050649589