Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors.
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Functional analysis of a frame-shift mutant of the dihydropyridine receptor pore subunit (alpha1S) expressing two complementary protein fragmentsModulation of L-type Ca2+ current but not activation of Ca2+ release by the gamma1 subunit of the dihydropyridine receptor of skeletal muscle3D Structure of the Dihydropyridine Receptor of Skeletal MuscleCa(V)1.1: The atypical prototypical voltage-gated Ca²⁺ channelA component of excitation-contraction coupling triggered in the absence of the T671-L690 and L720-Q765 regions of the II-III loop of the dihydropyridine receptor alpha(1s) pore subunit.Ca2+ sparks in embryonic mouse skeletal muscle selectively deficient in dihydropyridine receptor alpha1S or beta1a subunits.Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cellsNon-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling.Recovery of Ca2+ current, charge movements, and Ca2+ transients in myotubes deficient in dihydropyridine receptor beta 1 subunit transfected with beta 1 cDNA.Role of S4 segments and the leucine heptad motif in the activation of an L-type calcium channelRyanodine receptors: structure, expression, molecular details, and function in calcium release.Purification and characterization of ryanotoxin, a peptide with actions similar to those of ryanodine.Reduced Ca2+ current, charge movement, and absence of Ca2+ transients in skeletal muscle deficient in dihydropyridine receptor beta 1 subunit.The cardiac alpha(1C) subunit can support excitation-triggered Ca2+ entry in dysgenic and dyspedic myotubesMolecular origin of the L-type Ca2+ current of skeletal muscle myotubes selectively deficient in dihydropyridine receptor beta1a subunitDifferential regulation of skeletal muscle L-type Ca2+ current and excitation-contraction coupling by the dihydropyridine receptor beta subunit.Patch-clamp recording of charge movement, Ca2+ current, and Ca2+ transients in adult skeletal muscle fibersInvolvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscleCa2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.Truncation of the carboxyl terminus of the dihydropyridine receptor beta1a subunit promotes Ca2+ dependent excitation-contraction coupling in skeletal myotubes.Ca2+ current and charge movements in skeletal myotubes promoted by the beta-subunit of the dihydropyridine receptor in the absence of ryanodine receptor type 1.Cardiac-type EC-coupling in dysgenic myotubes restored with Ca2+ channel subunit isoforms alpha1C and alpha1D does not correlate with current densityCa2+-dependent excitation-contraction coupling triggered by the heterologous cardiac/brain DHPR beta2a-subunit in skeletal myotubesInvolvement of a heptad repeat in the carboxyl terminus of the dihydropyridine receptor beta1a subunit in the mechanism of excitation-contraction coupling in skeletal muscleFunctional interaction of CaV channel isoforms with ryanodine receptors studied in dysgenic myotubesMultiple loops of the dihydropyridine receptor pore subunit are required for full-scale excitation-contraction coupling in skeletal muscle.Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interactionCardiac stem cells.Amino acid residues 489-503 of dihydropyridine receptor (DHPR) β1a subunit are critical for structural communication between the skeletal muscle DHPR complex and type 1 ryanodine receptorCa(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.Rem uncouples excitation-contraction coupling in adult skeletal muscle fibers.Functional nonequality of the cardiac and skeletal ryanodine receptors.Accessibility of targeted DHPR sites to streptavidin and functional effects of binding on EC coupling.Single calcium channel behavior in native skeletal muscle.Unitary behavior of skeletal, cardiac, and chimeric L-type Ca2+ channels expressed in dysgenic myotubes.Role of calcium permeation in dihydropyridine receptor function. Insights into channel gating and excitation-contraction coupling.Functional impact of the ryanodine receptor on the skeletal muscle L-type Ca(2+) channelImpaired gating of an L-Type Ca(2+) channel carrying a mutation linked to malignant hyperthermia.Effects of inserting fluorescent proteins into the alpha1S II-III loop: insights into excitation-contraction coupling.Fibroblast growth factor homologous factors modulate cardiac calcium channels
P2860
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P2860
Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Relationship of calcium transi ...... iac dihydropyridine receptors.
@en
Relationship of calcium transi ...... iac dihydropyridine receptors.
@nl
type
label
Relationship of calcium transi ...... iac dihydropyridine receptors.
@en
Relationship of calcium transi ...... iac dihydropyridine receptors.
@nl
prefLabel
Relationship of calcium transi ...... iac dihydropyridine receptors.
@en
Relationship of calcium transi ...... iac dihydropyridine receptors.
@nl
P2093
P2860
P356
P1476
Relationship of calcium transi ...... iac dihydropyridine receptors.
@en
P2093
P2860
P304
P356
10.1085/JGP.103.1.125
P577
1994-01-01T00:00:00Z