about
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albuminLuciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitorsAntimicrobial peptides with stability toward tryptic degradation.High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms.Altered activity and physicochemical properties of short cationic antimicrobial peptides by incorporation of arginine analogues.Important structural features of 15-residue lactoferricin derivatives and methods for improvement of antimicrobial activity.Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics.Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic n glycans in alpha-mannosidosis: a method of monitoring treatment.Iterative Design and in Vivo Evaluation of an Oncolytic Antilymphoma Peptide.Discovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide.Syntheses and anti-tubercular activity of β-substituted and α,β-disubstituted peptidyl β-aminoboronates and boronic acids.Boron-containing peptidomimetics--a novel class of selective anti-tubercular drugs.Unnatural amino acid side chains as S1, S1', and S2' probes yield cationic antimicrobial peptides with stability toward chymotryptic degradation.The TNF Receptors p55 and p75 Mediate Chemotaxis of PMN Induced by TNFalpha and a TNFalpha 36-62 Peptide.The role of tryptophan in the antibacterial activity of a 15-residue bovine lactoferricin peptide.Bulky aromatic amino acids increase the antibacterial activity of 15-residue bovine lactoferricin derivatives.The effects of charge and lipophilicity on the antibacterial activity of undecapeptides derived from bovine lactoferricin.Simple parameterization of non-proteinogenic amino acids for QSAR of antibacterial peptides.Synthesis of a 2-arylsulphonylated tryptophan: the antibacterial activity of bovine lactoferricin peptides containing Trp(2-Pmc).Antimicrobial activity of short arginine- and tryptophan-rich peptides.Determination of absolute configuration and conformation of a cyclic dipeptide by NMR and chiral spectroscopic methods.Bulky nonproteinogenic amino acids permit the design of very small and effective cationic antibacterial peptides.Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis.Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity.Antifouling compounds from the sub-arctic ascidian Synoicum pulmonaria: synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues.Prediction of antibiotic activity and synthesis of new pentadecapeptides based on lactoferricins.Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion, and Relevance to Peptidic Systems.Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons.Metabolic fate of lactoferricin-based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability.Synthetic antimicrobial peptidomimetics with therapeutic potential.The pharmacophore of short cationic antibacterial peptides.Enhanced antitumor activity and selectivity of lactoferrin-derived peptides.A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation processA Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides fromThuiaria breitfussiFour-component relativistic chemical shift calculations of halogenated organic compoundsAbsolute Configuration of a Cyclic Dipeptide Reflected in Vibrational Optical Activity: Ab Initio and Experimental InvestigationDetermining the Absolute Configuration of Two Marine Compounds Using Vibrational Chiroptical SpectroscopyVery Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design Principles and Potential UsesIdentification of 3-oxodicarboxylic acids in human urineAbsolute configuration of 3-hydroxyadipic acid in human urine
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
John Sigurd Svendsen
@ast
John Sigurd Svendsen
@en
John Sigurd Svendsen
@es
John Sigurd Svendsen
@nl
John Sigurd Svendsen
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type
label
John Sigurd Svendsen
@ast
John Sigurd Svendsen
@en
John Sigurd Svendsen
@es
John Sigurd Svendsen
@nl
John Sigurd Svendsen
@sl
altLabel
John S. Mjøen Svendsen
@en
John S. Svendsen
@en
John Sigurd Svendsen
@en
prefLabel
John Sigurd Svendsen
@ast
John Sigurd Svendsen
@en
John Sigurd Svendsen
@es
John Sigurd Svendsen
@nl
John Sigurd Svendsen
@sl
P1053
F-1562-2017
P106
P1153
7102623190
P21
P31
P3829
P496
0000-0001-5945-6123