Expression, purification and kinetic characterization of wild-type human ornithine transcarbamylase and a recurrent mutant that produces 'late onset' hyperammonaemia.
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Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolutionHuman ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changesA single mutation in the active site swaps the substrate specificity ofN-acetyl-L-ornithine transcarbamylase andN-succinyl-L-ornithine transcarbamylaseX-ray structure and kinetic properties of ornithine transcarbamoylase from the human parasiteGiardia lambliaThe ygeW encoded protein from Escherichia coli is a knotted ancestral catabolic transcarbamylaseSubstrate-induced conformational change in a trimeric ornithine transcarbamoylase1.85-A resolution crystal structure of human ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiencyGenotype-Phenotype Correlations in Ornithine Transcarbamylase Deficiency: A Mutation UpdateAcetylornithine transcarbamylase: a novel enzyme in arginine biosynthesisStructure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis.A new mouse model of mild ornithine transcarbamylase deficiency (spf-j) displays cerebral amino acid perturbations at baseline and upon systemic immune activation.Sustained correction of OTC deficiency in spf( ash) mice using optimized self-complementary AAV2/8 vectors.Identification of a phosphinothricin-resistant mutant of rice glutamine synthetase using DNA shuffling.Crystal structure and biochemical properties of putrescine carbamoyltransferase from Enterococcus faecalis: Assembly, active site, and allosteric regulationA dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice.Stable overexpression of arginase I and ornithine transcarbamylase in HepG2 cells improves its ammonia detoxification.Arginine biosynthesis in Thermotoga maritima: characterization of the arginine-sensitive N-acetyl-L-glutamate kinaseExpression, purification, and characterization of recombinant human glutamine synthetase.Precision medicine in rare disease: Mechanisms of disparate effects of N-carbamyl-l-glutamate on mutant CPS1 enzymes.An in silico model of enterocytic glutamine to citrulline conversion pathway.'Late onset' ornithine transcarbamylase deficiency: function of three purified recombinant mutant enzymes.Estimation of the total number of disease-causing mutations in ornithine transcarbamylase (OTC) deficiency. Value of the OTC structure in predicting a mutation pathogenic potential
P2860
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P2860
Expression, purification and kinetic characterization of wild-type human ornithine transcarbamylase and a recurrent mutant that produces 'late onset' hyperammonaemia.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Expression, purification and k ...... 'late onset' hyperammonaemia.
@en
Expression, purification and k ...... 'late onset' hyperammonaemia.
@nl
type
label
Expression, purification and k ...... 'late onset' hyperammonaemia.
@en
Expression, purification and k ...... 'late onset' hyperammonaemia.
@nl
prefLabel
Expression, purification and k ...... 'late onset' hyperammonaemia.
@en
Expression, purification and k ...... 'late onset' hyperammonaemia.
@nl
P2093
P2860
P356
P1433
P1476
Expression, purification and k ...... 'late onset' hyperammonaemia.
@en
P2093
B S Rajagopal
C D Listrom
D Venugopal
H Morizono
M T McCann
N M Allewell
P2860
P304
P356
10.1042/BJ3220625
P407
P478
322 ( Pt 2)
P577
1997-03-01T00:00:00Z