Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.
about
An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic developmentGenetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans.SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans.Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Spindle assembly checkpoint genes reveal distinct as well as overlapping expression that implicates MDF-2/Mad2 in postembryonic seam cell proliferation in Caenorhabditis elegansHuman synthetic lethal inference as potential anti-cancer target gene detectionSynthetic lethality: general principles, utility and detection using genetic screens in human cellsSignificant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotesExploring the conservation of synthetic lethal genetic interaction networksSynthetic genetic targeting of genome instability in cancer.Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.The spindle assembly checkpoint in Caenorhabditis elegans: one who lacks Mad1 becomes mad oneKey players in chromosome segregation in Caenorhabditis elegans.Proposal for a new therapy for drug-resistant malaria using Plasmodium synthetic lethality inferenceComparative interaction networks: bridging genotype to phenotype.Synthetic lethality and cancer.Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans.Proper cyclin B3 dosage is important for precision of metaphase-to-anaphase onset timing in Caenorhabditis elegans.Synthetic lethal genetic interactions that decrease somatic cell proliferation in Caenorhabditis elegans identify the alternative RFC CTF18 as a candidate cancer drug target.Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion
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P2860
Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Synthetic lethal interactions ...... ssembly checkpoint components.
@en
Synthetic lethal interactions ...... ssembly checkpoint components.
@nl
type
label
Synthetic lethal interactions ...... ssembly checkpoint components.
@en
Synthetic lethal interactions ...... ssembly checkpoint components.
@nl
prefLabel
Synthetic lethal interactions ...... ssembly checkpoint components.
@en
Synthetic lethal interactions ...... ssembly checkpoint components.
@nl
P2093
P2860
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Synthetic lethal interactions ...... ssembly checkpoint components.
@en
P2093
Ann M Rose
Maja Tarailo
Sanja Tarailo
P2860
P304
P356
10.1534/GENETICS.107.080408
P407
P577
2007-12-01T00:00:00Z