Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease.
about
Mechanistic evidence in support of alpha1-antitrypsin as a therapeutic approach for type 1 diabetesExpanding the clinical indications for α(1)-antitrypsin therapyα1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.Testing agents for prevention or reversal of type 1 diabetes in rodents.α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejectionAlpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus.The impact of thiamine treatment in the diabetes mellitus.TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice.Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival.Effect of recombinant α1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.Exploration of α1-antitrypsin treatment protocol for islet transplantation: dosing plan and route of administration.Immune-modulating effects of alpha-1 antitrypsin.Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functionsImmune protective effect of human alpha-1-antitrypsin gene during β cell transplantation in diabetic mice.Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model.Targeting Innate Immunity for Type 1 Diabetes Prevention.Human α1-Antitrypsin Binds to Heat-Shock Protein gp96 and Protects from Endogenous gp96-Mediated Injury In vivoiTRAQ-Based Proteomics of Chronic Renal Failure Rats after FuShengong Decoction Treatment Reveals Haptoglobin and Alpha-1-Antitrypsin as Potential Biomarkers.Anti-inflammaging effects of human alpha-1 antitrypsin.Well-Known and Less Well-Known Functions of Alpha-1 Antitrypsin. Its Role in Chronic Obstructive Pulmonary Disease and Other Disease Developments.Novel therapeutic uses of alpha-1 antitrypsin: a window to the future.Alpha-1 antitrypsin therapy is safe and well tolerated in children and adolescents with recent onset type 1 diabetes mellitus
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P2860
Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@en
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@nl
type
label
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@en
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@nl
prefLabel
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@en
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@nl
P2093
P921
P1433
P1476
Intradermal alpha1-antitrypsin ...... OD mouse model of the disease.
@en
P2093
M Atkinson
P2888
P304
P356
10.1007/S00125-010-1829-2
P577
2010-07-01T00:00:00Z