Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.

Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.

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http://www.wikidata.org/entity/Q43000119
Substrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation ReactionsSpliceostatin hemiketal biosynthesis in Burkholderia spp. is catalyzed by an iron/α-ketoglutarate-dependent dioxygenase.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants.Diversity of P450 enzymes in the biosynthesis of natural productsCytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells.Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicinGenerate a bioactive natural product library by mining bacterial cytochrome P450 patterns.Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis.A metabolic gene cluster in Lotus japonicus discloses novel enzyme functions and products in triterpene biosynthesis.Expansion of chemical space for natural products by uncommon P450 reactions.Heterologous pathway assembly reveals molecular steps of fungal terreic acid biosynthesis.
P2860

Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.

Item
http://www.wikidata.org/entity/Q43000119
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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name
Cloning and characterization o ...... epoxidation and hydroxylation.
@en
Cloning and characterization o ...... epoxidation and hydroxylation.
@nl
type
label
Cloning and characterization o ...... epoxidation and hydroxylation.
@en
Cloning and characterization o ...... epoxidation and hydroxylation.
@nl
prefLabel
Cloning and characterization o ...... epoxidation and hydroxylation.
@en
Cloning and characterization o ...... epoxidation and hydroxylation.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Cloning and characterization o ...... epoxidation and hydroxylation.
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921