Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.
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Genome-wide association meta-analysis for total serum bilirubin levelsInherited disorders of bilirubin clearanceNew insights in bilirubin metabolism and their clinical implicationsOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRegulatable fatty acid transport mechanisms are central to the pathophysiology of obesity, fatty liver, and metabolic syndrome.The SLCO (former SLC21) superfamily of transporters.OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?Impact of OATP transporters on pharmacokinetics.Mitochondrial genome depletion dysregulates bile acid- and paracetamol-induced expression of the transporters Mdr1, Mrp1 and Mrp4 in liver cells.Effect of ursodeoxycholic acid treatment on the altered progesterone and bile acid homeostasis in the mother-placenta-foetus trio during cholestasis of pregnancy.Polymorphisms of SLC22A9 (hOAT7) in Korean Females with Osteoporosis.Differential expression of several drug transporter genes in HepG2 and Huh-7 cell lines.Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-infected adults.Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination.Active transport across the human placenta: impact on drug efficacy and toxicity.HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphismsOverexpression of OATP1B3 confers apoptotic resistance in colon cancer.The emerging importance of transporter proteins in the psychopharmacological treatment of the pregnant patient.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Excretion of biliary compounds during intrauterine life.Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibitionDrug transporters in the human blood-placental barrier.Pharmacogenetics of the organic anion transporting polypeptide 1A2The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acidHepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.Organic anion-transporting polypeptides.Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.Pharmacogenetics of drug-induced birth defects: the role of polymorphisms of placental transporter proteins.Prenatal exposure to common environmental factors affects brain lipids and increases risk of developing autism spectrum disorders.Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells.Role of OATP1B3 in the transport of bile acids assessed using first-trimester trophoblasts.Placental ABC Transporters: Biological Impact and Pharmaceutical Significance.Renal Drug Transporters and Drug Interactions.Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters.In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.Tissue distribution and phenobarbital induction of target SLC- and ABC- transporters in cattle.Excretion of fetal biliverdin by the rat placenta-maternal liver tandem.Membrane Transporters for Bilirubin and Its Conjugates: A Systematic Review.An advanced human in vitro co-culture model for translocation studies across the placental barrier.
P2860
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P2860
Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@en
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@nl
type
label
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@en
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@nl
prefLabel
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@en
Role of organic anion-transpor ...... pathway for foetal bilirubin.
@nl
P2860
P50
P356
P1433
P1476
Role of organic anion-transpor ...... y pathway for foetal bilirubin
@en
P2093
Oscar Briz
P2860
P304
P356
10.1042/BJ20030034
P407
P577
2003-05-01T00:00:00Z