Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. - Wikidata - awgldk - TriplyDB

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.

http://www.wikidata.org/entity/Q43009339

about

Diverse molecular targets for therapeutic strategies in Alzheimer's disease 5-HT6 receptors and Alzheimer's disease AVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders.Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat Idalopirdine as a treatment for Alzheimer's disease.Idalopirdine - a small molecule antagonist of 5-HT6 with therapeutic potential against obesity.The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment.Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models.The preclinical profile of asenapine: clinical relevance for the treatment of schizophrenia and bipolar mania.Latest treatment options for Alzheimer's disease, Parkinson's disease dementia and dementia with Lewy bodies.Psychopharmacology of atypical antipsychotic drugs: From the receptor binding profile to neuroprotection and neurogenesis.The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia.Investigational drugs targeting 5-HT6 receptors for the treatment of Alzheimer's disease.Potential serotonergic agents for the treatment of schizophrenia.Modulating 5-HT4 and 5-HT6 receptors in Alzheimer's disease treatment.AVN-492, A Novel Highly Selective 5-HT6R Antagonist: Preclinical Evaluation.Serotonin 5-HT6 Receptor Antagonists in Alzheimer's Disease: Therapeutic Rationale and Current Development Status.Emerging amyloid and tau targeting treatments for Alzheimer's disease.Emerging treatments for Alzheimer's disease for non-amyloid and non-tau targets.The 5-hydroxytryptamine (serotonin) receptor 6 agonist EMD 386088 ameliorates ketamine-induced deficits in attentional set shifting and novel object recognition, but not in the prepulse inhibition in rats.5-HT6 Receptor Agonist and Antagonist Against β-Amyloid-Peptide-Induced Neurotoxicity in PC-12 Cells.Idalopirdine, a selective 5-HT6 receptor antagonist, reduces food intake and body weight in a model of excessive eating.Design, synthesis and pharmacological evaluation of indolylsulfonamide amines as potent and selective 5-HT6 receptor antagonists.Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia.Restoration of physiological expression of 5-HT6 into the primary cilia of null mutant neurons lengthens both primary cilia and dendrites.

P2860

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P2860

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.

http://www.wikidata.org/entity/Q43009339

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

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Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

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type

label

Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

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Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

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prefLabel

Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

@en

Lu AE58054, a 5-HT6 antagonist ...... ject recognition test in rats.

@nl

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The International Journal of Neuropsychopharmacology

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Lu AE58054, a 5-HT6 antagonist ...... bject recognition test in rats

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Ben Grayson

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Bruno Giethlen

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David L McKinzie

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David L Nelson

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Franklin P Bymaster

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Jorn Arnt

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Louise M Witten

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Mads Kreilgaard

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Mette N Poulsen

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1021-1033

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scholarly article

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10.1017/S1461145710000659

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8

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Benny Bang-andersen

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2010-06-23T00:00:00Z

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20569520

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