Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts.
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Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNAEffect of distance between decaying (125)I and DNA on Auger-electron induced double-strand break yieldTripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B.Radioimmunotargeting of malignant glioma by monoclonal antibody D2C7 reactive against both wild-type and variant III mutant epidermal growth factor receptorsA stochastic cascade model for Auger-electron emitting radionuclides.Transcriptomic Signatures of Auger Electron Radioimmunotherapy Using Nuclear Targeting (111)In-Trastuzumab for Potential Combination Therapies.Intraperitoneal injection is not always a suitable alternative to intravenous injection for radiotherapyLocalized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted EffectsPreparation, cytotoxicity, and in vivo antitumor efficacy of 111In-labeled modular nanotransportersMolecular and cellular effects of Auger emitters: 2008-2011.Uptake, internalization and nuclear translocation of radioimmunotherapeutic agents.Triple targeting of Auger emitters using octreotate conjugated to a DNA-binding ligand and a nuclear localizing signal.Trastuzumab labeled to high specific activity with ¹¹¹In by conjugation to G4 PAMAM dendrimers derivatized with multiple DTPA chelators exhibits increased cytotoxic potency on HER2-positive breast cancer cells.¹¹¹In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: an Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer.Production and dosimetric aspects of the potent Auger emitter 58mCo for targeted radionuclide therapy of small tumors.Correlation between energy deposition and molecular damage from Auger electrons: A case study of ultra-low energy (5-18 eV) electron interactions with DNA.Toward intracellular targeted delivery of cancer therapeutics: progress and clinical outlook for brain tumor therapy.Development and preclinical studies of 64Cu-NOTA-pertuzumab F(ab')2 for imaging changes in tumor HER2 expression associated with response to trastuzumab by PET/CT.
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P2860
Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@en
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@nl
type
label
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@en
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@nl
prefLabel
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@en
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@nl
P2093
P1476
Antitumor effects and normal-t ...... uman breast cancer xenografts.
@en
P2093
Danny L Costantini
Katherine A Vallis
Kristin McLarty
Raymond M Reilly
P304
P356
10.2967/JNUMED.109.072389
P407
P577
2010-06-16T00:00:00Z