Context-dependent mutations predominate in an engineered high-affinity single chain antibody fragment.
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Thermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions.Computational design of antibody-affinity improvement beyond in vivo maturationAntibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sourcesDesign of peptide affinity ligands for S-protein: a comparison of combinatorial and de novo design strategies.Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions.Decreased secretion and unfolded protein response upregulation.Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chains.Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis.Phylogenetic divergence of CD47 interactions with human signal regulatory protein alpha reveals locus of species specificity. Implications for the binding site.
P2860
Q30374518-AD66448B-5CAE-46B0-B963-E3931315BEE2Q33576857-CDFF46CB-FE8F-4A72-B051-F864CC807132Q34460171-042A0F5D-9019-47A9-9766-428A5B38224AQ34637357-3A0A1E9E-2CFA-41F9-8B55-18D3CB5CC074Q35160784-82950D41-B6DC-48DE-AD83-28C8237EF18EQ36031460-A04C7205-E7B1-400C-A150-093283EA2F00Q39850882-D9466061-FFF1-482E-A517-0B566E262859Q41472386-A91CE092-BD44-45F0-8E0F-6CD01036B67DQ50708434-D965F400-CF84-4E19-9516-C92ECC0B6E89
P2860
Context-dependent mutations predominate in an engineered high-affinity single chain antibody fragment.
description
2006 nî lūn-bûn
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2006年の論文
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name
Context-dependent mutations pr ...... ingle chain antibody fragment.
@en
Context-dependent mutations pr ...... ingle chain antibody fragment.
@nl
type
label
Context-dependent mutations pr ...... ingle chain antibody fragment.
@en
Context-dependent mutations pr ...... ingle chain antibody fragment.
@nl
prefLabel
Context-dependent mutations pr ...... ingle chain antibody fragment.
@en
Context-dependent mutations pr ...... ingle chain antibody fragment.
@nl
P2860
P356
P1433
P1476
Context-dependent mutations pr ...... ingle chain antibody fragment.
@en
P2093
K Dane Wittrup
Katarina S Midelfort
P2860
P304
P356
10.1110/PS.051842406
P577
2006-02-01T00:00:00Z